- Palladium-catalyzed markovnikov terminal arylalkynes hydrostannation: Application to the synthesis of 1,1-diarylethylenes
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The palladium-catalyzed hydrostannation of terminal aryla-lkynes was achieved. The regioselectivity of the H-Sn bond addition across the triple bond was found to be controlled by an ortho substituent on the aromatic ring, whatever its electronic nature, to give exclusively α-branched vinylstan-nanes 2 in accordance with Markovnikov's rule. Subsequent Stille cross-coupling reaction of 2 with a variety of aryl halides readily provided, in moderate to good yields, a family of functionalized 1,1-diarylethylenes 1.
- Hamze, Abdallah,Veau, Damien,Provot, Olivier,Brion, Jean-Daniel,Alami, Mouad
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