Diarylmethylene disulfide compound as well as preparation method and application thereof
The invention relates to the technical field of medicines and in particular relates to a diarylmethylene disulfide compound as well as a preparation method and application thereof. An experiment result shows that on a cell model, the diarylmethylene disulfide compound provided by the invention has an effect of inhibiting neurotoxicity caused by excessive glutamic acid and an effect of inhibiting neurotoxicity caused by hydrogen peroxide; the diarylmethylene disulfide compound also has a platelet aggregation resisting effect and can be used for reducing a cerebral infarct area in a mouse MCAO (Middle Cerebral Artery Occlusion) model. The results show that the diarylmethylene disulfide compound provided by the invention can have prevention and/or treatment effects on cerebral stroke.
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Paragraph 0125; 0126; 0127; 0128; 0129
(2018/01/03)
Selective esterifications and acyl rearrangements in vitamin B6.
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Paul,Korytnyk
p. 1071 - 1087
(2007/10/04)
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