1104637-47-9 Usage
Uses
Used in Chemical Research:
Isopropenylboronic acid MIDA ester is used as a reactant for stereoretentive Suzuki-Miyaura coupling reactions. This application is crucial in the synthesis of complex organic molecules with specific stereochemistry, which is essential for the development of new drugs and materials.
Used in Pharmaceutical Development:
Isopropenylboronic acid MIDA ester is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its ability to participate in Suzuki cross-coupling with MIDA boronates allows for the creation of diverse molecular structures with potential therapeutic applications.
Used in Suzuki Cross-Coupling with MIDA Boronates:
Isopropenylboronic acid MIDA ester is used as a reactant in Suzuki cross-coupling reactions with MIDA boronates. This application is significant in the synthesis of complex organic molecules, as it enables the formation of carbon-carbon bonds with high selectivity and efficiency, which is vital for the development of new drugs and advanced materials in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1104637-47-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,4,6,3 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1104637-47:
(9*1)+(8*1)+(7*0)+(6*4)+(5*6)+(4*3)+(3*7)+(2*4)+(1*7)=119
119 % 10 = 9
So 1104637-47-9 is a valid CAS Registry Number.
1104637-47-9Relevant articles and documents
A general method for interconversion of boronic acid protecting groups: Trifluoroborates as common intermediates
Churches, Quentin I.,Hooper, Joel F.,Hutton, Craig A.
, p. 5428 - 5435 (2015/06/16)
We have developed a general protocol for the interconversion of diverse protected boronic acids, via intermediate organotrifluoroborates. N-Methyliminodiacetyl boronates, which have been hitherto resistant to direct conversion to trifluoroborates, have been shown to undergo fluorolysis at elevated temperatures. Subsequent solvolysis of organotrifluoroborates in the presence of trimethylsilyl chloride and a wide range of bis-nucleophiles enables the generation of a variety of protected boronic acids.
Methods for Forming Protected Organoboronic Acids
-
Page/Page column 19, (2011/09/14)
Described are methods of forming protected boronic acids that provide in a manner that is straightforward, scalable, and cost-effective a wide variety of building blocks, such as building blocks containing complex and/or pharmaceutically important structures, and/or provide simple or complex protected organoboronic acid building blocks. A first method includes reacting an imino-di-carboxylic acid and an organoboronate salt. A second method includes reacting a N-substituted morpholine dione and an organoboronic acid.
