110637-44-0

Basic information

• Product Name: (S)-1-(allyloxycarbonyl)pyrrolidine-2-carboxylic acid
• Synonyms: (S)-1-(allyloxycarbonyl)pyrrolidine-2-carboxylic acid
• CAS NO: 110637-44-0
• Molecular Formula: C₉H₁₃NO₄
• Molecular Weight: 199.20382
• Mol File: 110637-44-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-1-(allyloxycarbonyl)pyrrolidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(allyloxycarbonyl)pyrrolidine-2-carboxylic acid(110637-44-0)
• EPA Substance Registry System: (S)-1-(allyloxycarbonyl)pyrrolidine-2-carboxylic acid(110637-44-0)

Safety Data

• Hazardous Substances Data: 110637-44-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-1-(allyloxycarbonyl)pyrrolidine-2-carboxylic acid is used as a protecting group for the N-terminal amino acid in solid-phase peptide synthesis. It is favored for its ability to be easily removed under mild conditions, which is essential for the synthesis of complex peptide sequences and the development of peptide-based drugs.
Used in Chemical Biology Research:
Aoc-Pip is utilized as a key component in the synthesis of peptides for research purposes in chemical biology, where understanding the structure and function of peptides is critical for advancing the field.
Used in Medicinal Chemistry Research:
In medicinal chemistry, (S)-1-(allyloxycarbonyl)pyrrolidine-2-carboxylic acid is employed in the synthesis of peptides that have potential therapeutic applications, contributing to the discovery and design of new drugs.

Upstream product

• 2937-50-0 Allyl chloroformate 
• 147-85-3 L-proline 
• 71989-31-6 Fmoc-Pro-OH 

Downstream Products

• 147-85-3 L-proline 
• 190203-20-4 methyl 2(R)-{[2(R,S)-hydroxy-3(S)-({[1-(allyloxycarbonyl)pyrrolidin-2(S)-yl]carbonyl}amino)-6-({[(tert-butyloxycarbonyl)imino][(tert-butyloxycarbonyl)amino]methyl}amino)hexanoyl]amino}-3-phenylpropanoate 
• 190203-27-1 allyl 2(S)-(acetylamino)-3-[[4(S)-[(2(R)-{[2(R,S)-hydroxy-3(S)-({[1-(allyloxycarbonyl)pyrrolidin-2(S)-yl]carbonyl}amino)-6-({[(tert-butyloxycarbonyl)imino][(tert-butyloxycarbonyl)amino]methyl}amino)hexanoyl]amino}-3-phenylpropanoyl)amino]-5-[4-(tert-... 
• 190203-21-5 2(R)-{[2(R,S)-hydroxy-3(S)-({[1-(allyloxycarbonyl)pyrrolidin-2(S)-yl]carbonyl}amino)-6-({[(tert-butyloxycarbonyl)imino][(tert-butyloxycarbonyl)amino]methyl}amino)hexanoyl]amino}-3-phenylpropanoic acid 
• 190385-10-5 (2S,5S,11S,14R,17(R,S),18S)-N-<11-<4-(tert-butyloxy)benzyl>-14-benzyl-17-hydroxy-18-<<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>propyl>-4,8,13,16,20-pentaoxo-2,3,4,5,6,7,8,11,12,13,14,15,16,17,18,19,20,20a-octadeca... 
• 190203-31-7 (2S,5S,11S,14R,17(R,S),18S)-N-<11-<4-(tert-butyloxy)benzyl>-14-benzyl-17-hydroxy-18-<<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>propyl>-4,8,13,16,17,20-hexaoxo-2,3,4,5,6,7,8,11,12,13,14,15,16,17,18,19,20,20a-octadeca... 
• 129033-05-2 cyclotheonamide B 
• 813426-49-2 benzyl (2S)-N-allyloxycarbonylpyrrolidine-2-acetate 
• 610299-77-9 (S)-1-allylproline 

Relevant articles and documents

Synthesis of a PNA-encoded cysteine protease inhibitor library

Peptide nucleic acids (PNAs) have been used to encode a combinatorial library whereby each compound is labeled with a PNA tag which reflects its synthetic history and localizes the compound upon hybridization to an oligonucleotide array. We report herein

A new synthetic method for an indolizidine skeleton by C-N bond formation via a π-allylpalladium complex

Pd(0)-catalyzed intramolecular cyclic reaction via a π-allylpalladium complex provided an indolizidine skeleton in satisfactory high and reproducible yields by using allylic compound having an acetoxyl group as a leaving group. These results must be available for syntheses of various functional indolizidine alkaloids.

3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds

The invention relates to an antimicrobial compound of the formula: STR1 in which R1 is carboxy or protected carboxy, R2 is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl, R3 and R4 are each hydrogen or low