An efficient synthesis and antimicrobial studies of bioactive 4H-1,4-benzothiazine and their sulfone derivatives
4H-1,4-benzothiazines were prepared by condensation followed by oxidative cyclization of substituted 2-aminobenzenethiols with β-diketones in dimethylsulfoxide. On refluxing with 30% hydrogen peroxide in glacial acetic acid, 4H-1,4-benzothiazines yielded
SYNTHESIS OF 2-AMINO-3-FLUOROBENZENETHIOL AND ITS CONVERSION INTO DIFFERENT HETEROCYCLES
Heterocycles containing fluorine possess a variety of biological applications and are useful drugs. 5-Fluorouracil and 5-fluorotryptamine are eefective drugs used in the treatment of cancer.
Gupta, R. R.,Kumar, Rakesh
p. 229 - 240
(2007/10/02)
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