An efficient synthesis and antimicrobial studies of bioactive 4H-1,4-benzothiazine and their sulfone derivatives

Article abstract of DOI:10.1080/10426507.2012.740703

4H-1,4-benzothiazines were prepared by condensation followed by oxidative cyclization of substituted 2-aminobenzenethiols with β-diketones in dimethylsulfoxide. On refluxing with 30% hydrogen peroxide in glacial acetic acid, 4H-1,4-benzothiazines yielded