111380-63-3

Basic information

• Product Name: 1-{[3-(diethylamino)propyl]amino}-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol
• Synonyms: 5H-pyrido[4,3-b]indol-8-ol, 1-[[3-(diethylamino)propyl]amino]-4,5-dimethyl-
• CAS NO: 111380-63-3
• Molecular Formula: C₂₀H₂₈N₄O
• Molecular Weight: 340.4625
• Mol File: 111380-63-3.mol

Chemical Properties

• Boiling Point: 561.7°C at 760 mmHg
• Flash Point: 293.5°C
• Density: 1.15g/cm³
• Vapor Pressure: 3.2E-13mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 1-{[3-(diethylamino)propyl]amino}-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{[3-(diethylamino)propyl]amino}-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol(111380-63-3)
• EPA Substance Registry System: 1-{[3-(diethylamino)propyl]amino}-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol(111380-63-3)

Safety Data

• Hazardous Substances Data: 111380-63-3(Hazardous Substances Data)

Upstream product

• 111380-55-3 chloro-1 dimethyl-4,5 hydroxy-8-5H-pyrido <4,3-b> indole 
• 104-78-9 diethylaminopropylamine 
• 111380-50-8 4-methyl-8-methoxy-2H,5H-pyrido<4,3-b>indol-1-one 
• 111380-52-0 1-chloro-8-methoxy-4-methyl-5H-pyrido[4,3-b]-indole 
• 111380-54-2 1-chloro-4,5-dimethyl-8-methoxy-5H-pyrido[4,3-b]-indole 
• 111380-49-5 6,7,8,9-tetrahydro-8-methoxy-4-methyl-2H,5H-pyrido<4,3-b>indol-1-one 
• 95306-64-2 4-amino-5-methylpyridine-2(1H)-one 
• 111491-22-6 methyl-4 hydroxy-8-2H,5H-pyrido <4,3-b> indole-one-1 
• 111491-24-8 chloro-1 methyl-4 benzoyloxy-8-5H-pyrido <4,3-b> indole 
• 106-51-4 p-benzoquinone 
• 111491-25-9 chloro-1 dimethyl-4,5 benzoyloxy-8-5H-pyrido <4,3-b> indole 
• 111491-23-7 methyl-4 benzoyloxy-8-2H,5H-pyrido <4,3-b> indole-one-1 

Relevant articles and documents

Derivatives of pyridoindole, having anti-tumor properties

The present invention concerns derivatives of 5H-pyrido[4,3-b]-indole with the following general formula: STR1 in which n represents a whole number from 2 to 4, R1 represents hydrogen or a lower alkyl group; R2 represents hydrogen, a hydroxy group or a lower alkyloxy group; R3 and R4 represents hydrogen, a lower alkyl group or hydroxyalkyl group, R5 can be identical or different and represents hydrogen, a hydroxy group or a lower alkyl group, as well as the tautomeric forms and the addition salts with pharmaceutically acceptable mineral or organic acids. The invention also concerns their preparation process, and their use as medicaments.

1-Amino-Substituted 4-Methyl-5H-pyridoindoles (γ-Carbolines) as Tricyclic Analogues of Ellipticines: A New Class of Antineoplastic Agents

A series of 1-amino-substituted 4-methyl-5H-pyridoindoles that are structurally related to ellipticines by deletion of a ring have been synthesized in order to evaluate their DNA affinity, their in vitro cytotoxicity on L1210 cultured cells, and thei

SYNTHESE D'ANALOGUES TRICYCLIQUES DES ELLIPTICINES: LES METHYL-4,5H-PYRIDO INDOLES (γ-CARBOLINES) DIVERSEMENT SUBSTITUES SUR LEURS SOMMETS 1,5 ET 8.

Several ways to 1-functionnalized 4-methyl-5H-pyrido indoles have been worked out: a/ Starting from phenylhydrazines and 4-hydroxy-5-methyl-1H-pyridin-2-one 4 which react in boiling diphenylether giving directly 4-methyl-2H,5H-pyrido indol