111470-98-5

Basic information

• Product Name: 3-Ethyl-8-quinolinol
• Synonyms: 3-Ethyl-8-hydroxyquinoline;3-Ethyl-8-quinolinol;8-Quinolinol, 3-ethyl-
• CAS NO: 111470-98-5
• Molecular Formula: C11H11 N O
• Molecular Weight: 173.21
• Mol File: 111470-98-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Ethyl-8-quinolinol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethyl-8-quinolinol(111470-98-5)
• EPA Substance Registry System: 3-Ethyl-8-quinolinol(111470-98-5)

Safety Data

• Hazardous Substances Data: 111470-98-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Ethyl-8-quinolinol is used as a chelating agent for the analysis of metals, particularly in the pharmaceutical industry where it can help in the detection and quantification of trace metal contaminants in drugs and medicinal products.
Used in Agriculture:
In agriculture, 3-Ethyl-8-quinolinol is used as a chelating agent to improve the availability of essential metal nutrients to plants, enhancing their growth and development.
Used in Water Treatment Industry:
3-Ethyl-8-quinolinol is utilized in the water treatment industry as a chelating agent to remove heavy metal ions from water, contributing to the purification process and ensuring water safety.
Used in Medical Applications:
Due to its antimicrobial properties, 3-Ethyl-8-quinolinol is used as a potential candidate in medical applications, such as in the development of new antimicrobial agents to combat resistant bacterial strains.
Used in Cosmetic Applications:
3-Ethyl-8-quinolinol's anti-inflammatory properties make it a potential ingredient in cosmetic products, where it can be used to soothe and reduce inflammation in the skin.
However, it is crucial to handle 3-Ethyl-8-quinolinol with caution, as improper use may lead to harmful effects.

Upstream product

• 922-63-4 ethylacrolein 
• 95-55-6 2-amino-phenol 
• 88-75-5 2-hydroxynitrobenzene 
• 1004545-97-4 2-amino-3-hydroxybenzaldehyde 
• 123-72-8 butyraldehyde 
• 100-83-4 meta-hydroxybenzaldehyde 
• 42123-33-1 3-hydroxy-2-nitrobenzaldehyde 

Relevant articles and documents

Ozonolysis of Quinolines: A Versatile Synthesis of Polyfunctional Pyridines

A simple, safe and efficient procedure, easily adapted to a large scale, is described for the synthesis of substituted quinolines 2, which are readily oxidized by ozone in the presence of mineral acid, followed by an oxidative work up with hydrogen peroxide to afford substituted 2,3-pyridinedicarboxylic acids 3a-d,f and acyl pyridines 3e, g.

Microwave-enhanced Friedl?nder synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and tolerant bacteria

Herein, we disclose the development of a catalyst- and protecting-group-free microwave-enhanced Friedl?nder synthesis which permits the single-step, convergent assembly of diverse 8-hydroxyquinolines with greatly improved reaction yields over traditional oil bath heating (increased from 34% to 72%). This rapid synthesis permitted the discovery of novel biofilm-eradicating halogenated quinolines (MBECs = 1.0-23.5 μM) active against MRSA, MRSE, and VRE. These small molecules exhibit activity through mechanisms independent of membrane lysis, further demonstrating their potential as a clinically useful treatment option against persistent biofilm-associated infections.

A method for the sequential oxidation of substituted-8-hydroxy-quinolines to produce substituted-pyridine-2,3-dicarboxylic acids

The present invention provides a novel process for the preparation of substituted pyridine--2,3-dicarboxylic acids by the sequential peroxide--hypochlorite oxidations of substituted-8-hydroxy-quinolines.