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CAS

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1116136-19-6

Tert-butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate, commonly known as Carvedilol, is a pharmaceutical compound classified as a beta-blocker. It is utilized in the treatment of high blood pressure and heart failure, functioning by inhibiting the effects of adrenaline on the heart and blood vessels. This action results in lowered blood pressure, improved heart function, and a reduced risk of heart attacks and strokes. Carvedilol is available in tablet form and is frequently prescribed by medical professionals for the management of various cardiac conditions.

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  • 1116136-19-6 Structure

  • Basic information

    1. Product Name: tert-butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate
    2. Synonyms: tert-butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate
    3. CAS NO:1116136-19-6
    4. Molecular Formula: C13H17NO4
    5. Molecular Weight: 251.27838
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1116136-19-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 306.4±41.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.211±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 12.81±0.20(Predicted)
    10. CAS DataBase Reference: tert-butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate(CAS DataBase Reference)
    11. NIST Chemistry Reference: tert-butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate(1116136-19-6)
    12. EPA Substance Registry System: tert-butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate(1116136-19-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1116136-19-6(Hazardous Substances Data)

1116136-19-6 Usage

Uses

Used in Pharmaceutical Industry:
Tert-butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate is used as a medication for the treatment of high blood pressure and heart failure. It is employed for its ability to block the action of adrenaline on the heart and blood vessels, thereby lowering blood pressure, improving heart function, and reducing the risk of heart attacks and strokes.
Used in Cardiology:
In the field of cardiology, tert-butyl (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)carbamate is used as a beta-blocker to manage cardiac conditions. Its application helps in controlling the symptoms of high blood pressure and heart failure, providing therapeutic benefits to patients with these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1116136-19-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,1,6,1,3 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1116136-19:
(9*1)+(8*1)+(7*1)+(6*6)+(5*1)+(4*3)+(3*6)+(2*1)+(1*9)=106
106 % 10 = 6
So 1116136-19-6 is a valid CAS Registry Number.

1116136-19-6Downstream Products

1116136-19-6Relevant articles and documents

MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS

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Page/Page column 52, (2015/05/26)

The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.

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