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111908-94-2

2-(4-fluorophenyl)-3-(pyridin-4-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 111908-94-2 Structure

  • Basic information

    1. Product Name: 2-(4-fluorophenyl)-3-(pyridin-4-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
    2. Synonyms: 5H-Pyrrolo(1,2-a)imidazole, 2-(4-fluorophenyl)-6,7-dihydro-3-(4-pyridinyl)-
    3. CAS NO:111908-94-2
    4. Molecular Formula: C17H14FN3
    5. Molecular Weight: 279.3116
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 111908-94-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 457.2°C at 760 mmHg
    3. Flash Point: 230.3°C
    4. Appearance: N/A
    5. Density: 1.29g/cm3
    6. Vapor Pressure: 4.12E-08mmHg at 25°C
    7. Refractive Index: 1.672
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-(4-fluorophenyl)-3-(pyridin-4-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-(4-fluorophenyl)-3-(pyridin-4-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole(111908-94-2)
    12. EPA Substance Registry System: 2-(4-fluorophenyl)-3-(pyridin-4-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole(111908-94-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 111908-94-2(Hazardous Substances Data)

111908-94-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 111908-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,9,0 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 111908-94:
(8*1)+(7*1)+(6*1)+(5*9)+(4*0)+(3*8)+(2*9)+(1*4)=112
112 % 10 = 2
So 111908-94-2 is a valid CAS Registry Number.

111908-94-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-fluorophenyl)-3-pyridin-4-yl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole

1.2 Other means of identification

Product number -
Other names 2-(4-Fluorophenyl)-3-(4-pyridyl)-6,7-dihydro-[5H]-pyrrolo-[1,2-a]-imidazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:111908-94-2 SDS

111908-94-2Relevant articles and documents

Regulation of stress-induced cytokine production by pyridinylimidazoles inhibition of CSBP kinase

Gallagher, Timothy F.,Seibel, George L.,Kassis, Shouki,Laydon, Jeffrey T.,Blumenthal, Mary Jane,Lee, John C.,Lee, Dennis,Boehm, Jeffrey C.,Fier-Thompson, Susan M.,Abt, Jeffrey W.,Soreson, Margaret E.,Smietana, Juanita M.,Hall, Ralph F.,Garigipati, Ravi S.,Bender, Paul E.,Erhard, Karl F.,Krog, Arnold J.,Hofmann, Glenn A.,Sheldrake, Peter L.,McDonnell, Peter C.,Kumar, Sanjay,Young, Peter R.,Adams, Jerry L.

, p. 49 - 64 (2007/10/03)

Members of three classes of pyridinylimidazoles bind with varying affinities to CSBP (p38) kinase which is a member of a stress-induced signal transduction pathway. Based upon SAR and protein homology modeling, the pharmacophore and three potential modes of binding to the enzyme are presented. For a subset of pyridinylimidazoles, binding is shown to correlate with inhibition of CSBP kinase activity, whereas no significant inhibition of PKA, PKα and ERK kinase activity is observed.

Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages

-

, (2008/06/13)

A method of inhibiting the production of interleukin-1 by monocytes and/or macrophages in a human in need thereof which comprises administering to such a human an effective, interleukin-1 production inhibiting amount of a diaryl-substituted imidazole fuse

PYRROLO(1,2-A)IMIDAZOLE AND IMIDAZO(1,2-A)PYRIDINE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE PATHWAY INHIBITORS

-

, (2008/06/13)

Compounds comprising pyridyl and phenyl substituted pyrrolo[1,2-a]imidazole derivatives and pyridyl and phenyl substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions containing said compounds, and their use as 5-lipoxygenase pathway inhibitors.

Pyrrolo[1,2-a]imidazole and pyrrolo[1,2-a]pyridine derivatives and their use as 5-lipoxygenase pathway inhibitor

-

, (2008/06/13)

A method of inhibiting the production of 5-lipoxygenase products in an animal in need thereof which comprises administering an effective, 5-lipoxygenase pathway inhibiting amount of a 2(3)-(pyridyl)-3-(2)-substituted phenyl)-6,7-dihydro-[5H]-pyrrolo-[1,2-

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