111923-34-3

Basic information

• Product Name: Benzaldehyde, 2-ethyl-3-methyl- (9CI)
• Synonyms: Benzaldehyde, 2-ethyl-3-methyl- (9CI)
• CAS NO: 111923-34-3
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148.20168
• Product Categories: ALDEHYDE
• Mol File: 111923-34-3.mol

Chemical Properties

• Boiling Point: 232.7±9.0 °C(Predicted)
• Appearance: /
• Density: 0.986±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzaldehyde, 2-ethyl-3-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-ethyl-3-methyl- (9CI)(111923-34-3)
• EPA Substance Registry System: Benzaldehyde, 2-ethyl-3-methyl- (9CI)(111923-34-3)

Safety Data

• Hazardous Substances Data: 111923-34-3(Hazardous Substances Data)

Upstream product

• 111923-31-0 2-ethyl-3-methylacetanilide 
• 1576-87-0 trans-2-pentenal 
• 111923-33-2 2-ethyl-3-methylbenzonitrile 
• 111923-32-1 2-ethyl-3-methylaniline 
• 5779-93-1 2,3-dimethylbenzaldehyde 

Downstream Products

• 111923-35-4 1-(2'-ethyl-3'-methylphenyl)-4-methylpent-1-en-3-one 

Relevant articles and documents

Directed Metalation of Aromatic Aldimines with Lithium 2,2,6,6-Tetramethylpiperidide

N-Cyclohexyl aromatic aldimines are ortho-lithiated or o-methyl-lithiated with 2 equiv of lithium 2,2,6,6-tetramethylpiperidide (LTMP) in THF solution at -15 deg C.The lithiated intermediates generally reacted with alkyl halides or CO2 to provide ortho-functionalized aldimine products which could be readily converted to the corresponding aldehydes by hydrolysis with aqueous 4 M HCl.Aromatic aldimines derived from (+/-)-trans-2-methylcyclohexylamine or 3-amino-2,4-dimethylpentane are resistant toward C=N addition with 1 equiv of n-BuLi at 0 deg C in THF solution; however, they are also surprisingly resistant toward directed metalation reactions with either LTMP or n-BuLi.Exceptions to the ortho-directing and o-methyl-directing effects of the aldimine group were observed in a reaction of 3-methylthiophene-2-carboxaldehyde cyclohexylimine (7) with LTMP, followed by CH3I, which gave a 9:1 mixture of 3,5-dimethylthiophene-2-carboxaldehyde cyclohexylimine (22) and 5-ethyl-3-methylthiophene-2-carboxaldehyde cyclohexylimine (23), and a reaction of p-tolualdehyde 2,4-dimethylpent-3-ylimine (11) with either n-BuLi or LTMP, followed by CH3I, which gave p-ethylbenzaldehyde 2,4-dimethylpent-3-ylimine (25).

Synthesis of aromatic aldehydes by organocatalytic [4+2] and [3+3] cycloaddition of α,β-unsaturated aldehydes

Organocatalytic inter- and intramolecular [4+2] and [3+3] cycloadditions of α,β-unsaturated aldehydes to give polysubstituted aromatic aldehydes are described. High periselectivity for the cycloadditions, with catalyst effects exerted by l-proline and pyrrolidine-HOAc, as well as cocatalyst, additive effects, has been observed.

Synthetic Studies in Diterpene Series: Part XII - Synthesis of (+/-)-14-Ethyl-13-methylpodocarpa-8,11,13-triene - A Precursor of Veadeirol and Veadeiroic Acid

(+/-)-14-Ethyl-13-methylpodocarpa-8,11,13-triene (7) has been synthesised with a view to converting it into veadeirol (1) and veadeiroic acid (2), the two novel diterpenes having the rare cleistanthol skeleton.The key intermediate in the synthesis is 2-et