- Heterocyclic compound and preparation and application thereof
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The invention relates to bromodomain inhibitors, and provides a compound represented by a general formula I, a pharmaceutically acceptable salt, an enantiomer, a diastereoisomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method thereof, a pharmaceutical composition containing the same, and applicationthereof in pharmacy.
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Paragraph 0318-0320
(2020/07/24)
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- Facile oxidation of electron-poor benzo[b]thiophenes to the corresponding sulfones with an aqueous solution of H2O2 and P 2O5
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A facile oxidation for the clean conversion of benzo[b]thiophenes to their corresponding sulfones is described employing an aqueous solution of H 2O2 and P2O5; the solution can be prepared and stored on a multi-
- Antonow, Dyeison,Marrafa, Teresa,Dawood, Irfaan,Ahmed, Tauheed,Haque, Mohammad R.,Thurston, David E.,Zinzalla, Giovanna
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supporting information; experimental part
p. 2289 - 2291
(2010/07/08)
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- 1,3-Disubstituted benzazepines as novel, potent, selective neuropeptide Y Y1 receptor antagonists
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A novel series of potent and selective non-peptide neuropeptide Y (NPY) Y1 receptor antagonists, having benzazepine nuclei, have been designed, synthesized, and evaluated for activity. Chemical modification of the R1 and R3 substitue
- Murakami, Yasushi,Hara, Hirokazu,Okada, Tetsuo,Hashizume, Hiroshi,Kii, Makoto,Ishihara, Yasunobu,Ishikawa, Michio,Shimamura, Mayumi,Mihara, Shin-Inchi,Kato, Goro,Hanasaki, Kohji,Hagishita, Sanji,Fujimoto, Masafumi
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p. 2621 - 2632
(2007/10/03)
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