1128-89-8 Usage
Uses
Used in Pharmaceutical Industry:
1-Benzothiophene-5-carbonyl chloride is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its reactivity allows for the creation of new drug molecules with potential therapeutic applications, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Benzothiophene-5-carbonyl chloride is utilized as a reactive intermediate in the production of compounds that can be used in the development of pesticides and other agricultural chemicals, thereby playing a role in enhancing crop protection and yield.
Used in Organic Chemistry Research:
1-Benzothiophene-5-carbonyl chloride is employed as a valuable tool in organic chemistry research for exploring new synthetic pathways and developing innovative chemical reactions. Its strong nucleophilic reactivity makes it instrumental in expanding the scope of organic synthesis and the creation of complex molecular structures.
Used in the Synthesis of Heterocyclic Compounds:
As a versatile building block, 1-Benzothiophene-5-carbonyl chloride is used in the synthesis of heterocyclic compounds, which are important in various fields such as material science, pharmaceuticals, and agrochemicals due to their diverse chemical and biological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1128-89-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1128-89:
(6*1)+(5*1)+(4*2)+(3*8)+(2*8)+(1*9)=68
68 % 10 = 8
So 1128-89-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H5ClOS/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5H
1128-89-8Relevant academic research and scientific papers
Heterocyclic compound and preparation and application thereof
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Paragraph 0318-0320, (2020/07/24)
The invention relates to bromodomain inhibitors, and provides a compound represented by a general formula I, a pharmaceutically acceptable salt, an enantiomer, a diastereoisomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method thereof, a pharmaceutical composition containing the same, and applicationthereof in pharmacy.
Facile oxidation of electron-poor benzo[b]thiophenes to the corresponding sulfones with an aqueous solution of H2O2 and P 2O5
Antonow, Dyeison,Marrafa, Teresa,Dawood, Irfaan,Ahmed, Tauheed,Haque, Mohammad R.,Thurston, David E.,Zinzalla, Giovanna
supporting information; experimental part, p. 2289 - 2291 (2010/07/08)
A facile oxidation for the clean conversion of benzo[b]thiophenes to their corresponding sulfones is described employing an aqueous solution of H 2O2 and P2O5; the solution can be prepared and stored on a multi-
1,3-Disubstituted benzazepines as novel, potent, selective neuropeptide Y Y1 receptor antagonists
Murakami, Yasushi,Hara, Hirokazu,Okada, Tetsuo,Hashizume, Hiroshi,Kii, Makoto,Ishihara, Yasunobu,Ishikawa, Michio,Shimamura, Mayumi,Mihara, Shin-Inchi,Kato, Goro,Hanasaki, Kohji,Hagishita, Sanji,Fujimoto, Masafumi
, p. 2621 - 2632 (2007/10/03)
A novel series of potent and selective non-peptide neuropeptide Y (NPY) Y1 receptor antagonists, having benzazepine nuclei, have been designed, synthesized, and evaluated for activity. Chemical modification of the R1 and R3 substitue
