113121-36-1 Usage
Uses
Used in Pharmaceutical Industry:
3-Amino-6-(propylthio)pyridazine is utilized as a pharmaceutical intermediate for its potential role in the development of new drugs. Its unique structure allows it to serve as a building block in the synthesis of various bioactive molecules and pharmaceuticals, contributing to the advancement of medicinal treatments.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 3-Amino-6-(propylthio)pyridazine is employed as a key component in research aimed at discovering and designing novel therapeutic agents. Its chemical properties make it a suitable candidate for further modification and functionalization to enhance its pharmacological activity and selectivity.
Used in Organic Synthesis:
3-Amino-6-(propylthio)pyridazine is also used in organic synthesis as a versatile intermediate. Its reactivity and structural features enable the creation of a wide range of chemical entities, broadening the scope of potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Each application underscores the compound's significance in the development of innovative solutions across different sectors, highlighting its adaptability and the breadth of its utility in chemical and biological research.
Check Digit Verification of cas no
The CAS Registry Mumber 113121-36-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,1,2 and 1 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 113121-36:
(8*1)+(7*1)+(6*3)+(5*1)+(4*2)+(3*1)+(2*3)+(1*6)=61
61 % 10 = 1
So 113121-36-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H11N3S/c1-2-5-11-7-4-3-6(8)9-10-7/h3-4H,2,5H2,1H3,(H2,8,9)
113121-36-1Relevant articles and documents
A revision of the alcoholysis and alkanethiolysis of 3-amino-6-chloropyridazine
Maes,Lemiere,Dommisse,Haemers
, p. 1215 - 1218 (2001)
The synthesis of 3-amino-6-alkoxy- and 3-amino-6-alkylthiopyridazines via nucleophilic aromatic substitution on 3-amino-6-chloropyridazine is described. In contrast to literature reports, no pressure tube is required to perform these reactions.
2-Phenylimidazo[1,2-b]pyridazine derivatives highly active against Haemonchus contortus
Ali, Abdelselam,Cablewski, Teresa,Francis, Craig L.,Ganguly, Ashit K.,Sargent, Roger M.,Sawutz, David G.,Winzenberg, Kevin N.
scheme or table, p. 4160 - 4163 (2011/08/10)
A series of 2-phenylimidazo[1,2-b]pyridazine derivatives were synthesized and evaluated for their in vitro anthelmintic activity against Haemonchus contortus. The most active compounds had in vitro LD99 values of 30 nM, which is comparable to that of the benchmark commercial nematocide, Ivermectin.
CONTROL OF PARASITES IN ANIMALS BY THE USE OF IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVES
-
Page/Page column 31, (2008/06/13)
Novel imidazo[1,2-b]pyridazine compounds useful for controlling parasites in animals and methods of treatment of parasite infestation in animals using the compounds are disclosed. Formula (I).
Imidazopyridazines.II 6-Alkylthio- and 6-Arylthio-3-methoxy-2-phenylimidazopyridazines
Barlin, Gordon B.,Ireland, Stephen J.
, p. 1491 - 1497 (2007/10/02)
A series of 6-alkylthio- and 6-arylthio-3-methoxy-2-phenylimidazopyridazines has been prepared from 6-alkylthio- and 6-arylthio-pyridazin-3-amines through the corresponding 6-alkylthio- and 6-arylthio-2-phenylimidazopyridazin-3(5H)-ones.
