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1-Boc-3-(1-hydroxyethyl)-azetidine is a chemical compound characterized by the molecular formula C10H19NO3. It is a derivative of azetidine, a heterocyclic compound featuring a four-membered ring. The "1-Boc" in its name signifies the presence of a tert-butoxycarbonyl (Boc) protecting group attached to the nitrogen atom of the azetidine ring, which is crucial for protecting the nitrogen during chemical reactions. The "3-(1-hydroxyethyl)" component denotes a hydroxyethyl group at the C3 position of the azetidine ring, adding functionality and reactivity to the molecule. 1-Boc-3-(1-hydroxyethyl)-azetidine holds potential in the realms of organic synthesis and medicinal chemistry, with its specific applications and properties being contingent upon the intended use.

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  • 1138331-90-4 Structure
  • Basic information

    1. Product Name: 1-Boc-3-(1-hydroxyethyl)-azetidine
    2. Synonyms: 1-Boc-3-(1-hydroxyethyl)-azetidine;tert-butyl 3-(1-hydroxyethyl)azetidine-1-carboxylate
    3. CAS NO:1138331-90-4
    4. Molecular Formula: C10H19NO3
    5. Molecular Weight: 201.26276
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1138331-90-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-Boc-3-(1-hydroxyethyl)-azetidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-Boc-3-(1-hydroxyethyl)-azetidine(1138331-90-4)
    11. EPA Substance Registry System: 1-Boc-3-(1-hydroxyethyl)-azetidine(1138331-90-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1138331-90-4(Hazardous Substances Data)

1138331-90-4 Usage

Uses

Used in Organic Synthesis:
1-Boc-3-(1-hydroxyethyl)-azetidine is utilized as a synthetic intermediate for the preparation of various organic compounds. Its unique structure, including the Boc protecting group and the hydroxyethyl substituent, allows for selective reactions and the formation of complex molecules with specific functionalities.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Boc-3-(1-hydroxyethyl)-azetidine serves as a building block for the development of pharmaceutical agents. Its heterocyclic nature and the presence of a hydroxyethyl group enable the creation of bioactive molecules with potential therapeutic applications. The Boc protecting group can be selectively removed when necessary, unveiling the nitrogen atom for further reactions or interactions with biological targets.
Used in Pharmaceutical Industry:
1-Boc-3-(1-hydroxyethyl)-azetidine is employed as a key component in the synthesis of drug candidates. Its versatility in organic synthesis and compatibility with various chemical reactions make it a valuable asset in the design and production of new pharmaceuticals. 1-Boc-3-(1-hydroxyethyl)-azetidine's ability to be modified and functionalized according to specific requirements allows for the development of targeted therapies and improved drug delivery systems.
Used in Research and Development:
1-Boc-3-(1-hydroxyethyl)-azetidine is also used in research and development settings to explore its chemical properties and potential applications. Scientists and chemists investigate its reactivity, stability, and interactions with other molecules to uncover new ways to utilize it in the synthesis of novel compounds and the advancement of existing technologies.

Check Digit Verification of cas no

The CAS Registry Mumber 1138331-90-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,8,3,3 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1138331-90:
(9*1)+(8*1)+(7*3)+(6*8)+(5*3)+(4*3)+(3*1)+(2*9)+(1*0)=134
134 % 10 = 4
So 1138331-90-4 is a valid CAS Registry Number.

1138331-90-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 3-(1-hydroxyethyl)azetidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names 3-(1-hydroxyethyl)azetidine-1-carboxylic acid tert-butyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1138331-90-4 SDS

1138331-90-4Relevant articles and documents

ANTIDIABETIC COMPOUNDS

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Page/Page column 102, (2015/09/23)

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS

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Page/Page column 53-54, (2009/05/29)

A series of substituted aryl sulfone derivatives represented by Formula I, or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, calcium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, urinary incontinence, itchiness, allergic dermatitis, epilepsy, diabetic neuropathy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, sleep disorder, bipolar disorder and stroke, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds.

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