1142936-90-0

Basic information

• Product Name: N-[5-(4-methylphenyl)-[1,2,4]trithiazole[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
• Synonyms: N-[5-(4-methylphenyl)-[1,2,4]trithiazole[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
• CAS NO: 1142936-90-0
• Molecular Weight: 292.34
• Mol File: 1142936-90-0.mol

Chemical Properties

• CAS DataBase Reference: N-[5-(4-methylphenyl)-[1,2,4]trithiazole[1,5-a]pyridin-2-yl]cyclopropanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[5-(4-methylphenyl)-[1,2,4]trithiazole[1,5-a]pyridin-2-yl]cyclopropanecarboxamide(1142936-90-0)
• EPA Substance Registry System: N-[5-(4-methylphenyl)-[1,2,4]trithiazole[1,5-a]pyridin-2-yl]cyclopropanecarboxamide(1142936-90-0)

Safety Data

• Hazardous Substances Data: 1142936-90-0(Hazardous Substances Data)

Upstream product

• 5720-05-8 4-methylphenylboronic acid 
• 4023-34-1 cyclopropanecarboxylic acid chloride 
• 19798-81-3 2-Amino-6-bromopyridine 

Downstream Products

• 1206163-59-8 cyclopropanecarboxylic acid [5-(4-bromomethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-amide 

Relevant articles and documents

NOVEL PROCESS FOR THE PREPARATION OF FILGOTINIB AND INTERMEDIATES THEREOF

The present invention relates to a novel process for the preparation of filgotinib or a pharmaceutically acceptable salt and intermediates thereof which avoid Suzuki coupling reaction. (I)

Synthesis method of JAK1 inhibitor Filgotinib

The invention provides a preparing method of Filgotinib. The preparing method comprises the following steps that (1), 2-amino-6-bromopyridine reacts with a p-methylbenzene derivative to prepare a compound 1; (2), the compound 1 reacts with ethoxycarbonyl

[1,2,4]TRIAZOLO[1,5-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS AND THEIR USE

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain triazolo compounds (referred to herein as TAZ compounds), and especially certain [1,2,4]triazolo[1,5-a]pyridine and [1,2,4]triazolo[1,5-c]pyri