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CAS

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1144853-48-4

5-Thiomorpholinosulfonyl Isatin is a chemical compound that serves as an intermediate in the synthesis of Isatin sulfonamide analogs. It is a yellow solid with unique chemical properties that make it valuable in the field of pharmaceuticals and organic chemistry.

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  • 1144853-48-4 Structure

  • Basic information

    1. Product Name: 5-Thiomorpholinosulfonyl Isatin
    2. Synonyms: 5-Thiomorpholinosulfonyl Isatin;5-(4-ThioMorpholinylsulfonyl)-1H-indole-2,3-dione;5-ThioMorpholinosulfonyl-1H-indole-2,3-dione
    3. CAS NO:1144853-48-4
    4. Molecular Formula: C12H12N2O4S2
    5. Molecular Weight: 326.3482
    6. EINECS: N/A
    7. Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
    8. Mol File: 1144853-48-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: Dichloromethane, Ethyl Acetate, Methanol
    9. CAS DataBase Reference: 5-Thiomorpholinosulfonyl Isatin(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-Thiomorpholinosulfonyl Isatin(1144853-48-4)
    11. EPA Substance Registry System: 5-Thiomorpholinosulfonyl Isatin(1144853-48-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1144853-48-4(Hazardous Substances Data)

1144853-48-4 Usage

Uses

Used in Pharmaceutical Industry:
5-Thiomorpholinosulfonyl Isatin is used as an intermediate for the preparation of Isatin sulfonamide analogs, which are important compounds in the development of various pharmaceutical products. These analogs have potential applications in the treatment of different diseases due to their unique chemical structures and properties.
Used in Organic Chemistry:
In the field of organic chemistry, 5-Thiomorpholinosulfonyl Isatin is used as a key building block for the synthesis of complex organic molecules. Its unique structure allows for further functionalization and modification, making it a versatile compound for researchers and chemists working on the development of new chemical entities.

Check Digit Verification of cas no

The CAS Registry Mumber 1144853-48-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,4,8,5 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1144853-48:
(9*1)+(8*1)+(7*4)+(6*4)+(5*8)+(4*5)+(3*3)+(2*4)+(1*8)=154
154 % 10 = 4
So 1144853-48-4 is a valid CAS Registry Number.

1144853-48-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Thiomorpholinosulfonyl Isatin

1.2 Other means of identification

Product number -
Other names 5-thiomorpholin-4-ylsulfonyl-1H-indole-2,3-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1144853-48-4 SDS

1144853-48-4Relevant articles and documents

Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6

Chu, Wenhua,Rothfuss, Justin,Chu, Yunxiang,Zhou, Dong,Mach, Robert H.

supporting information; experimental part, p. 2188 - 2191 (2010/03/03)

A key step in the onset of Huntington's disease is the caspase-6 mediated cleavage of the protein huntingtin into toxic fragments. Therefore, the inhibition of caspase-6 has been identified as a target for therapeutic drug development for the treatment of

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