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1-(2-chlorophenyl)-2-piperazinone hydrochloride is a piperazine derivative chemical compound utilized in the pharmaceutical industry, known for its psychoactive properties and potential as a central nervous system stimulant. It serves as an intermediate in the synthesis of various pharmaceutical drugs and requires careful handling due to its potential to cause irritation.

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  • 1146411-40-6 Structure
  • Basic information

    1. Product Name: 1-(2-chlorophenyl)-2-piperazinonehydrochloride
    2. Synonyms: 1-(2-chlorophenyl)-2-piperazinonehydrochloride
    3. CAS NO:1146411-40-6
    4. Molecular Formula: C10H11ClN2O*ClH
    5. Molecular Weight: 247.12108
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1146411-40-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(2-chlorophenyl)-2-piperazinonehydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(2-chlorophenyl)-2-piperazinonehydrochloride(1146411-40-6)
    11. EPA Substance Registry System: 1-(2-chlorophenyl)-2-piperazinonehydrochloride(1146411-40-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1146411-40-6(Hazardous Substances Data)

1146411-40-6 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-chlorophenyl)-2-piperazinone hydrochloride is used as a chemical intermediate for the synthesis of various pharmaceutical drugs, contributing to the development of new medications.
Used in Research Settings:
In research, 1-(2-chlorophenyl)-2-piperazinone hydrochloride is used as a potential central nervous system stimulant, aiding in the study of psychoactive substances and their effects on the human body.
It is crucial to handle this compound with care, as it can cause skin or eye irritation, and should only be used by trained professionals in a controlled laboratory environment to ensure safety and proper application.

Check Digit Verification of cas no

The CAS Registry Mumber 1146411-40-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,6,4,1 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1146411-40:
(9*1)+(8*1)+(7*4)+(6*6)+(5*4)+(4*1)+(3*1)+(2*4)+(1*0)=116
116 % 10 = 6
So 1146411-40-6 is a valid CAS Registry Number.

1146411-40-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chlorophenyl)piperazin-2-one,hydrochloride

1.2 Other means of identification

Product number -
Other names AB1341

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1146411-40-6 SDS

1146411-40-6Relevant articles and documents

PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS

-

Page/Page column 180, (2011/05/06)

Provided are compounds of Formula (I) and/or Formula (II) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the Flaviviridae family of viruses such as hepatitis C virus (HCV).

Efficient synthesis of N-arylpiperazinones via a selective intramolecular Mitsunobu cyclodehydration

Weissman, Steven A.,Lewis, Stephanie,Askin, David,Volante,Reider, Paul J.

, p. 7459 - 7462 (2007/10/03)

A practical two pot synthesis of N-arylpiperazinones from the corresponding aniline is described. The key transformation is a selective intramolecular Mitsunobu cyclodehydration of an amidoalcohol intermediate. A series of N-arylpiperazinones were prepared in yields up to 89%.

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