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1147872-22-7

AM 103 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1H-Indole-2-propanoic acid, 3-[(1,1-dimethylethyl)thio]-1-[[4-(6-methoxy-3-pyridinyl)phenyl]methyl]-α,α-dimethyl-5-(2-pyridinylmethoxy)-, sodium salt (1:1)

    Cas No: 1147872-22-7

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  • 1H-Indole-2-propanoic acid, 3-[(1,1-dimethylethyl)thio]-1-[[4-(6-methoxy-3-pyridinyl)phenyl]methyl]-α,α-dimethyl-5-(2-pyridinylmethoxy)-, sodium salt (1:1)

    Cas No: 1147872-22-7

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  • 1147872-22-7 Structure

  • Basic information

    1. Product Name: AM 103
    2. Synonyms: AM 103;AM 103 (pharMaceutical)
    3. CAS NO:1147872-22-7
    4. Molecular Formula: C36H38N3O4S*Na
    5. Molecular Weight:
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1147872-22-7.mol

  • Chemical Properties

    1. Melting Point: 290 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: AM 103(CAS DataBase Reference)
    10. NIST Chemistry Reference: AM 103(1147872-22-7)
    11. EPA Substance Registry System: AM 103(1147872-22-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1147872-22-7(Hazardous Substances Data)

1147872-22-7 Usage

Uses

AM 103 is a novel inhibitor of 5-lipoxygenase-activating protein (FLAP).

Check Digit Verification of cas no

The CAS Registry Mumber 1147872-22-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,7,8,7 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1147872-22:
(9*1)+(8*1)+(7*4)+(6*7)+(5*8)+(4*7)+(3*2)+(2*2)+(1*2)=167
167 % 10 = 7
So 1147872-22-7 is a valid CAS Registry Number.

1147872-22-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name sodium,3-[3-tert-butylsulfanyl-1-[[4-(6-methoxypyridin-3-yl)phenyl]methyl]-5-(pyridin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoate

1.2 Other means of identification

Product number -
Other names UNII-FV4G3O3WI2

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1147872-22-7 SDS

1147872-22-7Downstream Products

1147872-22-7Relevant articles and documents

5-LIPOXYGENASE ACTIVATING PROTEIN (FLAP) INHIBITOR

-

Page/Page column 83, 88, (2009/05/30)

Described herein are methods for the synthesis of 3-[5-(pyridin-2-ylmethoxy)-3-(2-methyl-2-propylthio)-1-[4-(2-methoxypyridin-5-yl)benzyl]-indol-2-yl]-2,2-dimethyl-propionic acid, pharmaceutically acceptable salts, pharmaceutically acceptable solvates the

5-Lipoxygenase-activating protein inhibitors: Development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl] -5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)

Hutchinson, John H.,Li, Yiwei,Arruda, Jeannie M.,Baccei, Christopher,Bain, Gretchen,Chapman, Charles,Correa, Lucia,Darlington, Janice,King, Christopher D.,Lee, Catherine,Lorrain, Dan,Prodanovich, Pat,Rong, Haojing,Santini, Angelina,Stock, Nicholas,Prasit, Peppi,Evans, Jilly F.

body text, p. 5803 - 5815 (2010/03/24)

The potent and selective 5-lipoxygenase-activating protein leukotriene synthesis inhibitor 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)- benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (11j) is described. Lead optimizati

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