Synthesis, Conformation, and Immunosuppressive Activities of Three Analogues of Cyclosporin A Modified in the 1-Position
The syntheses of three new cyclosporin A (CsA) analogues that contain novel MeBmt derivatives in the 1-position are described.The MeBmt analogue that contains an additional methyl group on C4, (2S,3R,6E)-4,4-dimethyl-3-hydroxy-2-(N-methylamino)-6-octenoic
Aebi, Johannes D.,Deyo, Donald T.,Sun, Chong Qing,Guillaume, Dominique,Dunlap, Brian,Rich, Daniel H.
p. 999 - 1009
(2007/10/02)
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