1153291-65-6

Basic information

• Product Name: 2(3H)-Thiazolone, 4-(trifluoroMethyl)-
• Synonyms: 2(3H)-Thiazolone, 4-(trifluoroMethyl)-;CAS:1153291-65-6;4-(trifluoromethyl)-2(3H)-Thiazolone;4-Trifluoromethyl-thiazol-2-ol
• CAS NO: 1153291-65-6
• Molecular Formula: C4H2F3NOS
• Molecular Weight: 169.1249896
• Mol File: 1153291-65-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2(3H)-Thiazolone, 4-(trifluoroMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Thiazolone, 4-(trifluoroMethyl)-(1153291-65-6)
• EPA Substance Registry System: 2(3H)-Thiazolone, 4-(trifluoroMethyl)-(1153291-65-6)

Safety Data

• Hazardous Substances Data: 1153291-65-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
2(3H)-Thiazolone, 4-(trifluoroMethyl)is utilized as a building block in pharmaceutical research for the development of new drugs. Its trifluoromethyl group contributes to the enhancement of biological activity and metabolic stability, which is crucial for the effectiveness and safety of pharmaceutical compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 2(3H)-Thiazolone, 4-(trifluoroMethyl)is employed as a versatile intermediate for the preparation of a wide range of organic compounds. Its unique structure allows for various chemical reactions, facilitating the synthesis of complex molecules.
Used in Antimicrobial Applications:
2(3H)-Thiazolone, 4-(trifluoroMethyl)is studied for its potential as an antimicrobial agent, where it may be used to combat bacterial infections. Its ability to inhibit microbial growth makes it a candidate for further research and development in this area.
Used in Antitumor Applications:
2(3H)-Thiazolone, 4-(trifluoroMethyl)is also being investigated for its antitumor properties, with potential use in the development of cancer treatments. Its role in this application could involve targeting and inhibiting the growth of tumor cells.
Used in Antiviral Applications:
2(3H)-Thiazolone, 4-(trifluoroMethyl)is explored for its potential in antiviral research, where it may be employed to inhibit viral replication and reduce the severity of viral infections.
Used in Chemical Research:
In the broader field of chemical research, 2(3H)-Thiazolone, 4-(trifluoroMethyl)is used to study the properties of heterocyclic compounds and their potential applications in various chemical processes and reactions.

Upstream product

• 431-35-6 3-bromo-1,1,1-trifluoroacetone 
• 333-20-0 potassium thioacyanate 

Relevant articles and documents

Efficient Light-Induced pKa Modulation Coupled to Base-Catalyzed Photochromism

Photoswitchable acid–base pairs, whose pKa values can be reversibly altered, are attractive molecular tools to control chemical and biological processes with light. A significant, light-induced pKa change of three units in aqueous medium has been realized for two thermally stable states, which can be interconverted using UV and green light. The light-induced pKa modulation is based on incorporating a 3-H-thiazol-2-one moiety into the framework of a diarylethene photoswitch, which loses the heteroaromatic stabilization of the negatively charged conjugate base upon photochemical ring closure, and hence becomes significantly less acidic. In addition, the efficiency of the photoreactions is drastically increased in the deprotonated state, giving rise to catalytically enhanced photochromism. It appears that protonation has a significant influence on the shape of the ground- and excited-state potential energy surfaces, as indicated by quantum-chemical calculations.

TETRAZOLINONE COMPOUNDS AND ITS USE

The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein, R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, a C3-C12 cycloalkyl group or an adamantyl group, etc., which each optionally be substituted; R2 represents a hydrogen atom, an C1-C12 alkyl group, or a halogen atom, etc.; R4 and R5 represent independently of each other a hydrogen atom or an C1-C3 alkyl group, etc.; R6, R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, an C1-C12 alkyl group, a C1-C12 haloalkyl group, an C2-C12 alkenyl group, a C3-C12 cycloalkyl group, an C1-C12 alkoxy group or a C1-C12 haloalkoxy group, etc.; X and Y represent independently of each other a sulfur atom or an oxygen atom; Q represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.