116178-39-3Relevant articles and documents
PYRROLIDINONE DERIVATIVES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS
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Paragraph 0327; 0328, (2014/04/18)
The present invention relates to pyrrolidinone derivatives. The pyrrolidinone derivatives are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to t
PYRROLIDINONE DERIVATIVES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS
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Page/Page column 65; 67, (2014/05/07)
The present invention relates to pyrrolidinone derivatives of formula (I). The pyrrolidinone derivatives of formula (I) are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of pyrrolidinone derivatives as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
SYNTHESES OF 1,4-OXAZEPINES, AND THEIR 5-OXO DERIVATIVES FROM 2-PYRIDONES
Kurita, Jyoji,Yoneda, Takeharu,Kakusawa, Naoki,Tsuchiya, Takashi
, p. 3085 - 3088 (2007/10/02)
Thermolysis of the 3-aza-7-oxa- (11) and 3,7-diaza-4-oxotricyclo2,5>heptanes (12), prepared from 2-pyridones via four steps, resulted in valence isomerisation with ring opening to give the novel 1,4-oxazepin-5-ones (14) and 1,4-diazepin-5-ones (15), respectively, which were treated with triethyloxonium tetrafluoroborate to afford the fully unsaturated 1,4-oxazepines (16) and 1,4-diazepines (17), respectively.