116324-89-1

Basic information

• Product Name: pyridoxal 4-methoxybenzoyl hydrazone
• Synonyms: pyridoxal 4-methoxybenzoyl hydrazone
• CAS NO: 116324-89-1
• Molecular Formula: C₁₆H₁₇N₃O₄
• Molecular Weight: 315.32
• Mol File: 116324-89-1.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.29g/cm³
• Refractive Index: 1.604
• CAS DataBase Reference: pyridoxal 4-methoxybenzoyl hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: pyridoxal 4-methoxybenzoyl hydrazone(116324-89-1)
• EPA Substance Registry System: pyridoxal 4-methoxybenzoyl hydrazone(116324-89-1)

Safety Data

• Hazardous Substances Data: 116324-89-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H17N3O4/c1-10-15(21)14(12(9-20)7-17-10)8-18-19-16(22)11-3-5-13(23-2)6-4-11/h3-8,18,20H,9H2,1-2H3,(H,19,22)/b14-8+

Upstream product

• 66-72-8 pyridoxal 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 65-22-5 pyridoxal hydrochloride 

Relevant articles and documents

Suzuki-Miyaura cross-coupling reaction of aryl bromides catalyzed by palladium(II) pyridoxal hydrazone complexes

The reaction of [PdCl2(PPh3)2] and substituted pyridoxal hydrazone ligands (H2L) in methanol under reflux afford a series of palladium ONO coordinated complexes with general formula [Pd(PPh3)L] (where

Studies on Biologically Active Acylhydrazones. Part 1. Acid-Base Equilibria and Acid Hydrolysis of Pyridoxal Aroylhydrazones and Related Compounds

A series of pyridoxal aroylhydrazones has been synthesized and their UV, IR and 1H NMR spectra studied.In neutral methanol these hydrazones exist in the enolimine form, while in aqueous solution (pH ca.7.0) they exist predominantly in the zwitterionic form in which the phenolic proton is transferred to the pyridine nitrogen.Their aqueous acid-base equilibria show three successive steps for which protonation constants have been determined.The different acidity constants are correlated with Hammett substituent constants.The acid hydrolysis reactions of these hydrazones have also been investigated and the attack of a water molecule on the protonated azomethine seems to be the rate-controlling step.The hydrolysis reactions of N-salicylidene- and N-benzylidene-benzoylhydrazines have been studied for comparison.

Synthesis of New Acylhydrazones as Iron-Chelating Compounds

Fourteen acylhydrazides have been condensed with three aromatic o-hydroxy aldehydes (pyridoxal, salicylaldehyde, and 2-hydroxy-1-naphthaldehyde) to give 42 acylhydrazones, of which 38 are new.These compounds complex iron and have shown varying abilities to promote the movement of iron across biological membranes.Their infrared and nuclear magnetic resonance spectra support the structures assigned to them.