116476-54-1

Basic information

• Product Name: N,N''-BIS-(2,5-DICHLORO-PHENYL)-MALONAMIDE
• Synonyms: N,N'-bis(2,5-dichlorophenyl)propanediamide;Propanediamide, N1,N3-bis(2,5-dichlorophenyl)-
• CAS NO: 116476-54-1
• Molecular Formula: C₁₅H₁₀Cl₄N₂O₂
• Molecular Weight: 392.068
• Mol File: 116476-54-1.mol

Chemical Properties

• Boiling Point: 608.4 °C at 760 mmHg
• Flash Point: 321.7 °C
• Appearance: /
• Density: 1.582 g/cm³
• CAS DataBase Reference: N,N''-BIS-(2,5-DICHLORO-PHENYL)-MALONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N''-BIS-(2,5-DICHLORO-PHENYL)-MALONAMIDE(116476-54-1)
• EPA Substance Registry System: N,N''-BIS-(2,5-DICHLORO-PHENYL)-MALONAMIDE(116476-54-1)

Safety Data

• Hazardous Substances Data: 116476-54-1(Hazardous Substances Data)

Usage

Uses

Used in Coordination Chemistry:
N,N''-BIS-(2,5-DICHLORO-PHENYL)-MALONAMIDE is used as a ligand in coordination chemistry for its ability to form stable complexes with metal ions.
Used in Synthesis of Organic Compounds:
It is used as a building block for the synthesis of other organic compounds due to its unique structure and reactivity.
Used in Metal Ion Extraction and Separation:
N,N''-BIS-(2,5-DICHLORO-PHENYL)-MALONAMIDE is used as a chelating agent for the extraction and separation of metal ions in aqueous solutions, making it valuable in various industrial processes.
Used in Antimicrobial Applications:
It exhibits potential antimicrobial properties, making it a candidate for use in applications requiring the control of microbial growth.
Used in Chemical and Materials Science:
N,N''-BIS-(2,5-DICHLORO-PHENYL)-MALONAMIDE is utilized in various applications within the field of chemistry and materials science, including the development of new materials and chemical processes.

Upstream product

• 95-82-9 2,5 dichloroaniline 
• 105-53-3 diethyl malonate 
• 13195-64-7 diisopropyl malonate 

Downstream Products

• 102440-94-8 5,8-dichloro-4-(2,5-dichloro-anilino)-quinolin-2-ol 

Relevant articles and documents

Isopropyl N-arylmalonamates. Synthesis, structure, conformation and reactions with carbon disulfide

Acylation of aromatic amines 1 with diisopropyl malonate (2) leads to a mixture of isopropyl N-arylmalonamates 3 and malonanilides 4. The reaction of 3 with carbon disulfide in the presence of sodium hydride gives disodium salts 5. Treatment of 5 with an alkylating agent yields the open-chain or cyclic ketene dithioacetals 6, 7 or 8. The molecular structure, hydrogen bonding and preferential conformation of the isopropyl N-arylmalonamates 3, 6 and 7 were investigated using correlation analyses of IR, 13C NMR and AMI semiempirical data.

Synthesis of Benzo-halogenated 4-Hydroxy-2(1H)-quinolones

Malondianilides 3 derived from dichloro substituted anilines 2 undergo cyclization to afford 4-hydroxy-2(1H)-quinolones 4 in very good yields using methane sulfonic acid-phosphorus pentoxide as catalyst. 3,4-Dichloro anilines 5 can be shown to yield two i