116633-22-8Relevant articles and documents
Synthesis of Imidazo[1,2-a]pyridines and Imidazo[2,1-b]thiazoles Attached to a Cycloalkyl or Saturated Heterocycle Containing a Tertiary Hydroxy Substitution
Chenna Reddy,Patil, Vineetkumar B.,Nawaz Khan, Fazlur Rahman,Saravanan, Vadivelu
, p. 1486 - 1497 (2019/04/04)
A new method has been developed for the synthesis of imidazo[1,2-a]pyridines, imidazo[2,1-b]thiazoles, and benzo[d]imidazo[2,1-b]thiazoles attached to a cycloalkyl or saturated heterocycle containing a tertiary hydroxy substitution. Readily available substituted 2-aminopyridines, 2-aminothiazoles, and 2-aminobenzothiazoles were treated with bromohydroxycycloalkyl ethanones to afford the desired products in good yields.
Phenylsulphonyloxiranes as Functional Acyl Anion Equivalents in Organic Synthesis
Ashwell, Mark,Clegg, William,Jackson, Richard F. W.
, p. 897 - 908 (2007/10/02)
Phenylsulphonyloxiranes can be lithiated with butyllithium α to the phenylsulphonyl group at low temperature.The anions formed are unstable, but sufficiently reactive to allow the isolation of adducts in good yield following treatment with a variety of el
Phenylsulphonyl Oxirane: a Versatile Reagent for Organic Synthesis
Ashwell, Mark,Jackson, Richard F. W.
, p. 645 - 647 (2007/10/02)
Phenylsulphonyl oxirane (1) reacts as the synthetic equivalent of the acetaldehyde dipolar synthon (2).
