17356-19-3

Basic information

• Product Name: 1-ETHYNYLCYCLOPENTANOL
• Synonyms: 1-ethynyl-cyclopentano;Cyclopentanol, 1-ethynyl-;1-(1-ETHYNYL)-1-CYCLOPENTANOL;1-ETHYNYL-1-CYCLOPENTANOL;1-ETHYNYLCYCLOPENTANOL;Cyclopentanol, 1-ethynyl- (6CI, 7CI, 8CI, 9CI);1-ETHYNYL-1-CYCLOPENTANOL, 98+%;cyclopentyl ethynyl carbinol
• CAS NO: 17356-19-3
• Molecular Formula: C₇H₁₀O
• Molecular Weight: 110.15
• EINECS: 241-385-7
• Product Categories: Alkynes;Organic Building Blocks;Terminal;Building Blocks;Chemical Synthesis;Organic Building Blocks
• Mol File: 17356-19-3.mol
• Article Data: 22

Chemical Properties

• Melting Point: 27 °C
• Boiling Point: 156-159 °C(lit.)
• Flash Point: 120 °F
• Appearance: clear colorless to yellow liquid after melting
• Density: 0.962 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.1mmHg at 25°C
• Refractive Index: n20/D 1.474(lit.)
• Storage Temp.: Flammables area
• PKA: 13.34±0.20(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 1924167
• CAS DataBase Reference: 1-ETHYNYLCYCLOPENTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ETHYNYLCYCLOPENTANOL(17356-19-3)
• EPA Substance Registry System: 1-ETHYNYLCYCLOPENTANOL(17356-19-3)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37
• Safety Statements: 16-26-27-36/37/39
• RIDADR: UN 1986 3/PG 3
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 17356-19-3(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to yellow liquid after melting

Uses

1-Ethynylcyclopentanol is used in organic synthesis.

Synthesis Reference(s)

Synthetic Communications, 18, p. 131, 1988 DOI: 10.1080/00397918808077336

InChI:InChI=1/C7H10O/c1-2-7(8)5-3-4-6-7/h1,8H,3-6H2

Upstream product

• 4301-15-9 ethynyldimagnesium dibromide 
• 60-29-7 diethyl ether 
• 120-92-3 cyclopentanone 
• 1066-26-8 sodium acetylide 
• 74-86-2 acetylene 
• 65032-27-1 ethynylmagnesium chloride 
• 1066-54-2 trimethylsilylacetylene 
• 75-20-7 calcium carbide 
• 71321-24-9 1-<2-(Trimethylsilyl)ethynyl>cyclopentan-1-ol 
• 62785-89-1 (1-ethynylcyclopentyloxy)trimethylsilane 
• 4301-14-8 acetylenemagnesium bromide 
• 70277-75-7 lithium acetylide 
• 1216963-74-4 lithium acetylide-ethylenediamine complex 

Downstream Products

• 13562-17-9 5-(1-Hydroxy-cyclopentyl)-3-methyl-2-phenyl-pentin-⁽⁴⁾-diol-(2,3) 
• 40185-07-7 1-chloro-1-ethynylcyclopentane 
• 3859-35-6 1-vinyl-1-cyclopentanol 
• 149490-59-5 (C₆H₅)3SnC₂H₂C(OH)(CH₂)4 
• 149490-59-5 1-((E)-2-Triphenylstannanyl-vinyl)-cyclopentanol 
• 191791-53-4 (C₉H₇)Ru(((C₆H₅)2PCH₂)2)(CCHC₅H₇)⁽¹⁺⁾*PF₆^(1-)=[(C₉H₇)Ru(((C₆H₅)2PCH₂)2)(CCHC₅H₇)]PF₆ 
• 180848-42-4 mer-[(1,2-bis(diphenylphosphino)ethane)(CO)3W=C=CHC=CH(CH₂)3] 
• 228259-91-4 (Z)-1-[2-(tri-p-tolylstannyl)vinyl]-1-cyclopentanol 
• 149669-80-7 (Z)-1-[2-(triphenylstannyl)vinyl]-1-cyclopentanol 
• 1064-10-4 hexaphenylditin 
• 1029358-05-1 (4-{5-[2-(1-hydroxycyclopentyl)-1-ethynyl]-2-pyridyl}piperazino)-2-trifluoromethylphenylmethanone 
• 160327-08-2 (Z)-1-[2-(iododiphenylstannyl)vinyl]-1-cyclopentanol 
• 211819-31-7 (Z)-1-[2-(dichlorophenylstannyl)vinyl]-1-cyclopentanol 
• 211819-32-8 (Z)-1-[2-(dichloro-p-tolylstannyl)vinyl]-1-cyclopentanol 

Relevant articles and documents

Halogen-Substituted Allenyl Ketones through Ring Opening of Nonstrained Cycloalkanols

An efficient synthesis of halogen-substituted allenyl ketones via Ag-catalyzed oxidative ring opening of allenyl cyclic alcohols under mild reaction conditions has been achieved. The reaction features a wide substrate scope and excellent regioselectivity. The synthetic potential of the products has been demonstrated by their conversion to stereodefined alkenes and heterocyclic compounds.

ETHERS AND ESTERS OF 1-SUBSTITUTED CYCLOALKANOLS FOR USE AS AROMA CHEMICALS

The present invention relates to the use of an ether or an ester of a 1 -substituted cycloalkanol or of mixtures of two or more ethers or esters of 1 -substituted cycloalkanols or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof as aroma chemicals; to the use thereof for modifying the scent character of a fragranced composition; to an aroma chemical composition containing an ether or an ester of a 1 -substituted cycloalkanol or of mixtures of two or more ethers or esters of 1 -substituted cycloalkanols or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof; and to a method of preparing a fragranced composition or for modifying the scent character of a fragranced composition. The invention further relates to specific ethers or esters of 1 -substituted cycloalkanols.

Opioid receptor agonists and application thereof

The invention discloses compounds and salts thereof that can be used as opioid receptor ligands, a preparation method of the compounds, compositions containing the compounds, and a use of the compounds as [mu] opioid receptor agonists; the compounds are used for treatment of [mu] opioid receptor-mediated related diseases, such as pains and pain-related disorders.