Structure-activity relationships in 1,4-benzodioxan-related compounds. Investigation on the role of the dehydrodioxane ring on α1-adrenoreceptor blocking activity
Several analogues of 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]methyl]-1,4-benzodioxan (WB 4101, 1) were prepared and evaluated for their blocking activity on α1- and α2-adrenoreceptors in the isolated rat vas deferens. The results we