116680-33-2

Basic information

• Product Name: 1H-IMidazole,2-Methyl-1-(2-Methylpropyl)- (Related Reference)
• Synonyms: 1H-IMidazole,2-Methyl-1-(2-Methylpropyl)- (Related Reference);1H-IMidazole,2-Methyl-1-(2-Methylpropyl)-;1-Isobutyl-2-MethyliMidazole;1-isobutyl-2-methyl-1H-imidazole
• CAS NO: 116680-33-2
• Molecular Formula: C₈H₁₄N₂
• Molecular Weight: 138.21016
• Mol File: 116680-33-2.mol

Chemical Properties

• Boiling Point: 225-256 °C
• Appearance: /
• Density: 0.94±0.1 g/cm3(Predicted)
• PKA: 7.80±0.31(Predicted)
• CAS DataBase Reference: 1H-IMidazole,2-Methyl-1-(2-Methylpropyl)- (Related Reference)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-IMidazole,2-Methyl-1-(2-Methylpropyl)- (Related Reference)(116680-33-2)
• EPA Substance Registry System: 1H-IMidazole,2-Methyl-1-(2-Methylpropyl)- (Related Reference)(116680-33-2)

Safety Data

• Hazardous Substances Data: 116680-33-2(Hazardous Substances Data)

Usage

Uses

1H-Imidazole,2-Methyl-1-(2-methylpropyl)(Related Reference) is used as a chemical intermediate in the synthesis of various compounds. Its specific application reason is due to its unique structure and reactivity, which can be utilized in the creation of new molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
1H-Imidazole,2-Methyl-1-(2-methylpropyl)(Related Reference) is used as a building block for the development of new pharmaceutical compounds. Its unique structure allows for the creation of molecules with potential therapeutic properties, contributing to the advancement of drug discovery and development.
Used in Chemical Research:
1H-Imidazole,2-Methyl-1-(2-methylpropyl)(Related Reference) is used as a research tool in chemical studies. Its distinct chemical properties make it a valuable compound for understanding the behavior of imidazole derivatives and their potential applications in various fields.

Synthetic route

1-isobutyl 2-methylimidazole (116680-33-2) + 4-bromobenzenecarbonitrile (623-00-7) → 4-(3-isobutyl-2-methylimidazol-4-yl)benzonitrile (1201005-90-4)

Conditions	Yield
With potassium acetate; palladium diacetate In ISOPROPYLAMIDE at 150℃; for 17h; Inert atmosphere; regioselective reaction;	71%

1-isobutyl 2-methylimidazole (116680-33-2) + triethylene glycol mono(butyl)ether phosphoric acid ester ammonium salt → C20H43O10P*C8H14N2

Conditions	Yield
In toluene at 120℃; for 3h;

1-isobutyl 2-methylimidazole (116680-33-2) + diethylene glycol mono(hexyl)ether phosphoric acid ester ammonium salt → C20H43O8P*C8H14N2

Conditions	Yield
In toluene at 120℃; for 3h;

1-isobutyl 2-methylimidazole (116680-33-2) + 2-ammonium sulfoethyl methacrylate (52556-35-1) → C6H10O5S*C8H14N2

Conditions	Yield
In ethanol at 50℃; for 3h;

Downstream Products

• 1201005-90-4 4-(3-isobutyl-2-methylimidazol-4-yl)benzonitrile 

Relevant articles and documents

Amine catalyst for producing polyurethane and polyisocyanurate

An amine catalyst-for production of a polyurethane and a polyisocyanurate is provided which comprises a quaternary ammonium compound represented by General Formula (1): where R1 to R6 are independently a linear or branched saturated hydrocarbon group of 1 to 4 carbon atoms; R7 and R8 are independently a linear or branched, saturated or unsaturated hydrocarbon group of 2 to 12 carbon atoms; n is a number of 0 to 3 provided that at n=o any one of R1, R2 and R3, and R5 and/or R6 may be linked together to form a heterocycle, or at n=1, 2, or 3, R5 or R6 and R4 may be linked together to form a heterocycle; A is a carbonate group or an organic acid group; and X is number of 1 to 2. The catalyst has high activity in formation of polyurethane foams and polyisocyanurate foams, having less odor, and producing foams of high fire retardance, having high curability, high retarding effect, and low corrosiveness.