cas 116834-64-1, 4-[(8-QUINOLINYLSULFONYL)AMINO]BENZOIC ACID | Articles data ｜lookchem

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116834-64-1

Articles about 116834-64-1Total 11 be found

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CRYSTALLINE FORMS OF N-(4-(4-(CYCLOPROPYLMETHYL) PIPERAZINE-1-CARBONYL)PHENYL)QUINOLINE-8-SULFONAMIDE
Provided herein are amorphous and crystalline hemisulfate salt forms of the formula (I). Also provided are pharmaceutical compositions comprising the amorphous and crystalline hemisulfate salt forms, methods for their manufacture, and uses thereof for tre
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(2019/06/11)

Pyruvate kinase activators for use in therapy
Described herein are methods for using compounds that activate pyruvate kinase.
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Page/Page column 186

(2016/08/29)

Methods of using pyruvate kinase activators
Described herein are methods for using compounds that activate pyruvate kinase.
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(2016/08/23)

THERAPEUTIC COMPOUNDS AND COMPOSITIONS
Compounds of general formula (I) and compositions comprising compounds of general formula I that modulate pyruvate kinase are described herein. Also described herein are methods of using the compounds that modulate pyruvate kinase in the treatment of diseases.
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Page/Page column 126

(2014/09/29)

THERAPEUTIC COMPOUNDS AND COMPOSITIONS
Compounds of general formula I: and compositions comprising compounds of general formula I that modulate pyruvate kinase are described herein. Also described herein are methods of using the compounds that modulate pyruvate kinase in the treatment of diseases.
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Paragraph 0463

(2014/09/30)

THERAPEUTIC COMPOUNDS AND COMPOSITIONS
Compounds of general formula (I) and compositions comprising compounds of general formula (I) that modulate pyruvate kinase are described herein. Also described herein are methods of using the compounds that modulate pyruvate kinase in the treatment of diseases.
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Page/Page column 140

(2014/09/29)

THERAPEUTIC COMPOUNDS AND COMPOSITIONS AND THEIR USE AS PKM2 MODULATORS
Compositions comprising compounds of general formula (I) that modulate pyruvate kinase are described herein. Also described herein are methods of using the compounds that modulate pyruvate kinase in the treatment of diseases.
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Page/Page column 52; 53

(2014/05/24)

THERAPEUTIC COMPOUNDS AND COMPOSITIONS
Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
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Page/Page column 62

(2012/07/14)

NOVEL N- (4- (AZETIDINE - 1 - CARBONYL) PHENYL) - (HETERO - ) ARYLSULFONAMIDE DERIVATIVES AS PYRUVATE KINASE M2 (PMK2) MODULATORS
Compounds of general Formula (I), and compositions comprising compounds of general formula I that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of canc
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(2012/06/30)

THERAPEUTIC COMPOUNDS AND COMPOSITIONS
Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
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Page/Page column 89

(2011/01/05)

Benzamidoaldehydes and their use as cysteine protease inhibitors
Compounds of the formula where R1, R2, R3, X and n are as defined in the description, are inhibitors of cysteine protease.
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(2008/06/13)

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Chemical Properties

Melting Point: 260-269℃
Boiling Point: 585.1±56.0 °C(Predicted)
Density: 1.503±0.06 g/cm3(Predicted)
PKA: 4.00±0.10(Predicted)
PSA: 104.74000
LogP: 3.88760

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