117391-09-0Relevant articles and documents
Free-radical based cycloalkanol synthesis and annulation from thioacetal precursors
Yadav, Veejendra,Fallis, Alex G.
, p. 779 - 789 (2007/10/02)
A general procedure for the synthesis of diverse cyclopentanols via free-radical cyclization of unsaturated 1,3-oxathiolanes and 1,3-oxathiolan-5-ones is described.The scope of these reactions, including preliminary rate studies that indicate that the 1,3-oxathiolan-5-ones cyclize at a useful rate (1.4*106 M-1s-1 at 80 deg C), has been examined.This permits the rapid assembly, by intramolecular annulation, of various additional ring systems, including bicyclooctanols, bicyclononanols, and bicyclooctanols for use in total synthesis. Key words: radical cyclization, oxathiolanes, oxathiolanones.
CYCLOPENTANE SYNTHESIS and ANNULATION: INTRAMOLECULAR RADICAL CYCLIZATION of ACETALS
Yadav, Veejendra K.,Fallis, Alex G.
, p. 897 - 900 (2007/10/02)
A general procedure for cyclopentane synthesis based on free-radical cyclization of thioacetals is described.This permits the rapid assembly, by intamolecular annulation, of various ring systems bearing useful functionality for use in total synthesis.