Solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines by grindstone chemistry
The present work describes the solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines in excellent to nearly quantitative yields from 2-aminopyridines and a wide variety of ω-bromomethylketones using a grindstone procedure at 25°C to 30°C for 3 to
Godugu, Kumar,Nallagondu, Chinna Gangi Reddy
p. 250 - 259
(2020/10/23)
Solvent- and catalyst-free synthesis of imidazo[1,2-a]pyridines under microwave irradiation
A facile solvent- and catalyst-free method for the synthesis of a series of imidazo[1,2-a]pyridines in good to excellent yields by the condensation of 2-aminopyridines with α-bromoketones under microwave irradiation has been developed. The important featu