- TIMOSAPONIN COMPOUNDS
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Provided herein are timosaponin compounds of Frmula I, II, IIΙ, I', II' and IIΙ', pharmaceutical compositions comprising the coumpounds, and processes of preparation thereof. Also provided are uses of said timosaponin compounds for preparing medicament for the treatment of diseases associated with beta-amyloid in hosts or subjects in need thereof.
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- Total synthesis of a furostan saponin, timosaponin BII
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The natural timosaponin BII, (25S)-26-O-β-D-glucopyranosyl-22-hydroxy- 5β-furostane-3β,26-diol-3-O-β-D-glucopyranosyl-(1→2) -β-D-galactopyranoside, isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), has been efficiently synthesized
- Cheng, Shuihong,Du, Yuguo,Ma, Baiping,Tan, Dawei
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experimental part
p. 3112 - 3118
(2011/02/26)
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