- Synthesis of saponins using partially protected glycosyl donors
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(Matrix Presented) A new class of glycosyl donors having unprotected 2- and 2,4-hydroxyl groups were investigated under the standard glycosylation conditions. This approach was shown to be generally effective for the synthesis of alkyl and steroidal glyco
- Du, Yuguo,Gu, Guofeng,Wei, Guohua,Hua, Yuxia,Linhardt, Robert J.
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- Efficient one-pot synthesis of tigogenin saponins and their antitumor activities
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An efficient synthesis of naturally occurring tigogenin triglycoside 1a and its three derivatives 1b-d bearing different carbohydrate moieties, as well as their antitumor activities, is described. Partially protected thiogalactosides bearing unprotected 2
- Gu, Guofeng,An, Lian,Fang, Min,Guo, Zhongwu
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- TIMOSAPONIN COMPOUNDS
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Provided herein are timosaponin compounds of Frmula I, II, IIΙ, I', II' and IIΙ', pharmaceutical compositions comprising the coumpounds, and processes of preparation thereof. Also provided are uses of said timosaponin compounds for preparing medicament for the treatment of diseases associated with beta-amyloid in hosts or subjects in need thereof.
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Paragraph 00190
(2013/10/22)
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