118754-52-2

Basic information

• Product Name: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde
• Synonyms: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde
• CAS NO: 118754-52-2
• Molecular Formula: C₈H₃Cl₂F₃O
• Molecular Weight: 243.0100296
• Mol File: 118754-52-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde(118754-52-2)
• EPA Substance Registry System: 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde(118754-52-2)

Safety Data

• Hazardous Substances Data: 118754-52-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,6-Dichloro-4-trifluoroMethyl-benzaldehyde is used as a key intermediate in organic synthesis for the creation of a variety of complex organic compounds. Its unique structure and reactivity allow for the formation of diverse chemical entities, contributing to the advancement of chemical research and development.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde is employed as a precursor in the synthesis of various medicinal compounds. Its presence in the molecular structure can impart specific therapeutic properties, making it a valuable component in drug discovery and formulation.
Used in Agrochemical Development:
2,6-Dichloro-4-trifluoroMethyl-benzaldehyde also finds application in the agrochemical sector, where it is used in the development of pesticides and other crop protection agents. Its chemical properties can be leveraged to enhance the effectiveness of these products, ensuring better agricultural yields and protection against pests.
Used in Specialty Chemicals Manufacturing:
2,6-Dichloro-4-trifluoroMethyl-benzaldehyde is utilized in the production of specialty chemicals that cater to specific industrial needs. Its unique characteristics make it suitable for applications in various niche markets, such as the development of high-performance materials and advanced chemical formulations.
Safety Precautions:
Due to its high reactivity, 2,6-Dichloro-4-trifluoroMethyl-benzaldehyde should be handled and stored with extreme care. Proper safety measures, including the use of personal protective equipment and adherence to established safety protocols, are essential to minimize potential hazards associated with this compound.

Upstream product

• 2591-86-8 N-Formylpiperidine 
• 118754-53-3 2-bromo-1,3-dichloro-5-(trifluoromethyl)benzene 
• 68-12-2 N,N-dimethyl-formamide 
• 54773-20-5 1,3-dichloro-5-(trifluoromethyl)benzene 

Downstream Products

• 118754-34-0 2-(2,6-dichloro-4-trifluoromethylphenyl)-4-methylimidazole 
• 118754-23-7 D-2-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylimidazole 
• 1414931-76-2 Methyl 3'-chloro-2'-formyl-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate 
• 1414931-43-3 3-(2'-(((2-chloro-2'-methyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)amino)methyl)-3'-isopropyl-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-ylcarboxamido)propanoic acid 
• 1414931-81-9 ethyl 3-(2'-(((2-chloro-2'-methyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)amino)methyl)-3'-isopropyl-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-ylcarboxamido)propanoate 
• 1415130-47-0 ethyl 3-(5-(3-chloro-2-formyl-5-(trifluoromethyl)phenyl)picolinamido)propanoate 

Relevant articles and documents

BIPHENYL DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS

The present invention is directed to biphenyl derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.

CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS

The present invention relates to the use of a compound of formula I wherein R1, R2, R3, R4, X and n are as defined herein or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomers and/or optical isomers for the treatment of psychoses, pain, dysfunction in memory and learning, attention deficit, schizophrenia, dementia disorders or Alzheimer's disease.

CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS

The present invention relates to the use of a compound of general formula (I) wherein R1/R2 are independently from each other hydrogen, lower alkyl, -CH2)o-cycloalkyl for o being 0 or 1, or are benzyl or heterocycloalkyl; or R1 and R2 are together with the N-atom to which they are attached a ring containing -(CH2)3-, -(CH2)4-, -(CH2)5-, -(CH2)2-O-(CH2)2-, -(CH2)2-S-(CH2)2-, -(CH2)2-NR-(CH2)2-, -(CH2)2-C(O)-(CH2)2-, -(CH2)2-CF2-(CH2)2-, -CH2-CHR-(CH2)2, -CHR-(CH2)3, CHR-(CH2)2-CHR-, or is the ring 2,6-diaza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester and R is hydroxy, halogen, cycloalkyl, or C(O)O-lower alkyl; X is -(CH2)4-, -(CH2)3-, -(CH2)2- or -CH2-; R3 is S-lower alkyl, CF3, OCHF2, lower alkoxy, lower alkyl, phenyl, cycloalkyl or halogen; R4 is CF3, lower alkoxy, lower alkyl, halogen and n is 1 or 2; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomers and/or optical isomers thereof for the manufacture of a medicament for the treatment of psychoses, pain, dysfunction in memory and learning, attention deficit, schizophrenia, dementia disorders or Alzheimer's disease.

Pyrazole derivatives and insecticidal compositions containing the derivative as active component

A pyrazole derivative represented by the formula (1) is low in toxicity and persistence and yet has an extremely high insecticidal efficacy STR1 wherein A is CH, N or C-halogen atom, R1 is hydrogen atom, lower alkyl, lower haloalkyl, benzyl or

Pesticidal method using 2-phenylimidazole derivatives

The invention provides a method for the control of arthropod, plant nematode, helminth or protozoan pests using a 2-phenylimidazole derivative of the formula: STR1 wherein R1 represents hydrogen, alkyl (optionally substituted by alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, carboxy or alkoxycarbonyl), R2 and R3, each represents hydrogen, halogen, nitro, carboxy, cyano, alkoxycarbonyl, alkanoyl, or optionally alkyl substituted carbamoyl or sulphamoyl, or amino (optionally substituted by alkyl, alkoxycarbonyl or alkanoyl) or a group R, RO, RS, RSO or RSO2 in which R represents alkyl (optionally substituted by halogen), and Ar represents a group of the formula: STR2 wherein R4 and R6 each represents halogen or a group R, RO, RS, RSO or RSO2, and R5, R7 and R8 each represents a substituent as defined for R4 and R6, or represents hydrogen, hydroxy, carboxy, nitro, cyano, amino, alkylamino (optionally substituted by alkyl, alkoxycarbonyl or alkanoyl), alkoxycarbonyl or alkanoyl or a pesticidally acceptable salt thereof, with the exclusion of compounds in which R2 and R3 simultaneously represent hydrogen atoms, compositions for use in the method and novel compounds of formula I.

Nuclear-fluorinated trifluoromethylbenzaldehydes

Process for the preparation of nuclear-fluorinated trifluoromethylbenzaldehydes from nuclear-chlorinated trifluoromethylbenzaldehydes, and new nuclear-fluorinated trifluoromethylbenzaldehydes.