1414931-76-2

Upstream product

• 118754-52-2 2,6-dichloro-4-(trifluoromethyl)benzaldehyde 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 

Downstream Products

• 1414931-81-9 ethyl 3-(2'-(((2-chloro-2'-methyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)amino)methyl)-3'-isopropyl-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-ylcarboxamido)propanoate 
• 1414931-43-3 3-(2'-(((2-chloro-2'-methyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)amino)methyl)-3'-isopropyl-5'-(trifluoromethyl)-[1,1'-biphenyl]-4-ylcarboxamido)propanoic acid 

Relevant academic research and scientific papers

BIPHENYL DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS

The present invention is directed to biphenyl derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.