1189561-66-7

Basic information

• Product Name: (S)-Gossypol (acetic acid)
• Synonyms: (S)-Gossypol (acetic acid)
• CAS NO: 1189561-66-7
• Molecular Formula: C₂H₄O₂*C₃₀H₃₀O₈
• Molecular Weight: 578.61
• Mol File: 1189561-66-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-Gossypol (acetic acid)(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-Gossypol (acetic acid)(1189561-66-7)
• EPA Substance Registry System: (S)-Gossypol (acetic acid)(1189561-66-7)

Safety Data

• Hazardous Substances Data: 1189561-66-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-Gossypol (acetic acid) is used as an anti-cancer agent for its potential to inhibit the growth of various cancer cell lines. It is being studied for its effectiveness in treating different types of cancer, given its ability to target and suppress the proliferation of cancer cells.
Used in Contraceptive Development:
In the contraceptive industry, (S)-Gossypol (acetic acid) is utilized for its anti-fertility effects, as it has been shown to reduce sperm motility and act as a spermicide. This property makes it a candidate for the development of male contraceptives or other fertility control methods.
Used in Agricultural Industry:
While not explicitly mentioned in the provided materials, given its spermicidal effects, (S)-Gossypol (acetic acid) could potentially be used in the agricultural industry as a non-hormonal pesticide to control certain pests, particularly if they are affected by its contraceptive properties.

Upstream product

• 303-45-7 (rac)-gossypol 
• 64-19-7 acetic acid 

Downstream Products

• 784206-41-3 apogossypol 
• 114309-69-2 1,1‘,6,6’,7,7’-hexahydroxy-5,5’-diisopropyl-3,3-dimethyl-2,2’-binaphthalene-8-carbaldehyde 
• 105201-55-6 acetic acid 1,7,1',6',7'-pentaacetoxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthalenyl-6-yl ester 
• 4649-82-5 6,6',7,7'-Tetrahydroxy-5,5'-diisopropyl-3,3'-dimethyl-8,8'-bis-(phenylimino-methyl)-(2,2'-binaphthalin)-1,1',4,4'-tetraon 
• 4547-72-2 gossypolone 
• 303-45-7 (rac)-gossypol 

Relevant articles and documents

A gossypol derivatives and their use in inhibiting urease activity

The invention relates to the technical field of fertilizer, and particularly relates to gossypol derivatives and an application thereof in inhibition of urease activity. The gossypol derivatives have the chemical structural general formula described in the specification, wherein R represents a part except amino in amino acid, and the amino acid is amino acid containing primary amino. The gossypol derivatives take gossypol as an aldehyde group providing reagent and are prepared by modifying the aldehyde group of gossypol with the amino of the amino acid. When the gossypol derivatives are applied in preparation of urease inhibitors, the urease inhibition effect is good, and the IC50 value inhibiting soil ammonia volatilization effect is as low as 1.56*10 mol.L. Compared with a gossypol raw material, the gossypol derivatives have better solubility, are more stable and are convenient to use; and a part of gossypol derivatives have the urease inhibition activity significantly enhanced.

PRODUCTION OF GOSSYPOL CO-CRYSTALS

This invention relates to relates to methods for producing gossypol acetic acid co- crystals and (-)-gossypol acetic acid co-crystals. The invention also relates to pharmaceutical compositions comprising gossypol acetic acid co-crystals and (-)-gossypol a