- NOVEL BICYCLIC HETEROCYCLIC COMPOUND
-
Provided are a novel compound having a superior inhibitory action on KAT-II, a production method thereof, use thereof, and a pharmaceutical composition containing the aforementioned compound and the like. A compound represented by the formula (I) or a pharmacologically acceptable salt thereof. wherein each symbol is as defined in the DESCRIPTION.
- -
-
Paragraph 0499; 0500
(2018/09/27)
-
- BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY
-
The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
- -
-
-
- SUBSTITUTED 4-(SELENOPHEN-2(OR-3)-YLAMINO)PYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF
-
Selenophene compounds of formula (I) are described herein. In the compounds of Formula (I), ring A is a 6-membered aromatic fused ring, optionally containing one, two or three nitrogen atoms; a 5-membered heteroaromatic fused ring; or a mono- or bicyclic
- -
-
Paragraph 0319
(2013/10/22)
-
- ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
-
The present invention is for the anti-inflammatory compounds that have an inhibitory activity against protein tyrosine kinases and their pharmaceutical composition(s) containing the compound as the active ingredient. Since the compounds of the present invention can inhibit multiple protein kinases associated with inflammatory diseases and immune disorders, they are useful for their prevention or treatment.
- -
-
Paragraph 0318; 0323; 0324
(2013/03/28)
-
- CHEMICAL COMPOUNDS
-
The use of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein X1, X2, X3, X4, Ra, p, R1,Z,Y, R2, R3 and R4 are as d
- -
-
-
- Thiazole Derivatives, VII. - Synthesis of Thiazolopyrimidine Derivatives
-
The 2-alkylthio-4-aminothiazoles 1a-k are converted into thiazolopyrimidines 2a-f, 3, 5, 7a, and 7b.Compound 1a reacts with formamide to give 2a after two hours at 200 deg C, but after eight hours at 200 deg C 3 is the resulting product.Reactions o
- Wobig, Dieter
-
p. 409 - 412
(2007/10/02)
-