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3-cyclopropylpyrazin-2-amine is a heterocyclic amine with the molecular formula C7H9N3. It features a cyclopropyl ring and a pyrazine ring in its structure, and contains a nitrogen atom with a lone pair of electrons, classifying it as a potential base. This chemical compound serves as a building block in organic synthesis and has been explored for its potential in pharmacological applications due to its unique structure and reactivity, garnering interest among researchers in organic and medicinal chemistry.

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  • 1190969-76-6 Structure
  • Basic information

    1. Product Name: 3-cyclopropylpyrazin-2-amine
    2. Synonyms: 3-cyclopropylpyrazin-2-amine
    3. CAS NO:1190969-76-6
    4. Molecular Formula: C7H9N3
    5. Molecular Weight: 135.16646
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 1190969-76-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 269.1±40.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.273±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 3.56±0.10(Predicted)
    10. CAS DataBase Reference: 3-cyclopropylpyrazin-2-amine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-cyclopropylpyrazin-2-amine(1190969-76-6)
    12. EPA Substance Registry System: 3-cyclopropylpyrazin-2-amine(1190969-76-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1190969-76-6(Hazardous Substances Data)

1190969-76-6 Usage

Uses

Used in Organic Synthesis:
3-cyclopropylpyrazin-2-amine is used as a building block in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for the formation of diverse chemical entities, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3-cyclopropylpyrazin-2-amine is used as a starting material for the development of new pharmaceutical compounds. Its derivatives have been investigated for their potential therapeutic properties, including possible applications in the treatment of various diseases and disorders.
Used in Research and Development:
3-cyclopropylpyrazin-2-amine is utilized in research and development settings to explore its chemical properties and reactivity. This helps in understanding its potential applications and limitations, as well as in the design of new synthetic routes and methodologies in organic chemistry.
Used in Drug Discovery:
3-cyclopropylpyrazin-2-amine is employed in drug discovery processes to identify and optimize lead compounds with potential therapeutic effects. Its unique structural features make it a promising candidate for the development of novel drugs with improved efficacy and selectivity.
Used in Chemical Education:
In chemical education, 3-cyclopropylpyrazin-2-amine can be used as a teaching aid to illustrate the concepts of heterocyclic amines, organic synthesis, and medicinal chemistry. It provides a practical example of how chemical structures can influence reactivity and potential applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 1190969-76-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,0,9,6 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1190969-76:
(9*1)+(8*1)+(7*9)+(6*0)+(5*9)+(4*6)+(3*9)+(2*7)+(1*6)=196
196 % 10 = 6
So 1190969-76-6 is a valid CAS Registry Number.

1190969-76-6Upstream product

1190969-76-6Downstream Products

1190969-76-6Relevant articles and documents

Imidazo-pyrazine derivatives as potent CXCR3 antagonists

Du, Xiaohui,Gustin, Darin J.,Chen, Xiaoqi,Duquette, Jason,McGee, Lawrence R.,Wang, Zhulun,Ebsworth, Karen,Henne, Kirk,Lemon, Bryan,Ma, Ji,Miao, Shichang,Sabalan, Emmanuel,Sullivan, Timothy J.,Tonn, George,Collins, Tassie L.,Medina, Julio C.

scheme or table, p. 5200 - 5204 (2010/03/24)

A general way of improving the potency of CXCR3 antagonists with fused hetero-bicyclic cores was identified. Optimization efforts led to the discovery of a series of imidazo-pyrazine derivatives with improved pharmacokinetic properties in addition to increased potency. The efficacy of the lead compound 21 is evaluated in a mouse lung inflammation model.

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