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Tetrahydro-3-methyl-4H-pyran-4-one, commonly known as maltol, is a naturally occurring organic compound characterized by its sweet, caramel-like odor. It is widely recognized for its aromatic properties and is frequently utilized in various industries for its pleasant aroma and taste.

119124-53-7

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119124-53-7 Usage

Uses

Used in Food and Beverage Industry:
Tetrahydro-3-methyl-4H-pyran-4-one is used as a flavoring agent for its sweet, caramel-like aroma, enhancing the taste and smell of baked goods, candies, and tobacco products.
Used in Cosmetic and Personal Care Industry:
In cosmetic and personal care products, Tetrahydro-3-methyl-4H-pyran-4-one is used as a fragrance ingredient to impart a pleasant scent, making the products more appealing to consumers.
Used in Pharmaceutical and Nutraceutical Industry:
Tetrahydro-3-methyl-4H-pyran-4-one is studied for its potential antioxidant and anti-inflammatory properties, indicating its use as a therapeutic agent in the development of pharmaceutical and nutraceutical products.

Check Digit Verification of cas no

The CAS Registry Mumber 119124-53-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,1,2 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 119124-53:
(8*1)+(7*1)+(6*9)+(5*1)+(4*2)+(3*4)+(2*5)+(1*3)=107
107 % 10 = 7
So 119124-53-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O2/c1-5-4-8-3-2-6(5)7/h5H,2-4H2,1H3

119124-53-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Methyldihydro-2H-pyran-4(3H)-one

1.2 Other means of identification

Product number -
Other names 3-methyloxan-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119124-53-7 SDS

119124-53-7Relevant articles and documents

Aminopyridyloxypyrazole derivative and preparation method and application thereof

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Paragraph 0075; 0382-0387, (2021/05/19)

The invention relates to an aminopyridyloxypyrazole derivative and a preparation method and application thereof. The structure of the aminopyridyloxypyrazole derivative is shown as a formula (I). The invention provides a brand-new aminopyridyloxypyrazole derivative which has obvious effects of inhibiting TGF [beta] R1 (ALK5) kinase activity and treating cancer or fibrosis related diseases, and the preparation method of the derivative is simple and easy to operate.

Selective α-Methylation of Ketones

Frolov, Andriy I.,Ostapchuk, Eugeniy N.,Pashenko, Alexander E.,Chuchvera, Yaroslav O.,Rusanov, Eduard B.,Volochnyuk, Dmitriy M.,Ryabukhin, Sergey V.

, p. 7333 - 7346 (2021/06/28)

The convenient and scalable preparative approach for the two-step α-methylation of ketones is described. The optimized protocols for regioselective preparation of enaminones with further diastereoselective and functional groups tolerant hydrogenation to α-methylketones are developed. The scope and limitations of the proposed methodology are discussed. The advantages compared to known procedures are demonstrated. The unexpected role of acetone in the hydrogenation is suggested. The evaluation of the method for both early building block synthesis and late-stage CH-functionalization is shown. The elaborate procedures' preparability and scalability are demonstrated by the synthesis of several α-methyl ketones up to 100 g amount.

Preparation method and application of key intermediate of non-opioid analgesic

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Paragraph 0054; 0055; 0064; 0065; 0090; 0091, (2019/08/01)

Dihydro-4-acetal-2H-pyran-3(4H)-one (compound II) is used as a raw material, and the raw material and methyltriphenylphosphine bromide are subjected to a Wittig reaction to obtain a compound III; thedouble bond of the compound III is subjected to a reduction reaction to obtain a compound IV; the compound IV is subjected to acetal hydrolysis under the action of a dilute acid to generate a compoundV; the compound V and benzylamine are subjected to nucleophilic addition reaction to generate a compound VI; and finally, debenzylating and hydrochloride forming are carried out, so that a non-opioidanalgesic key intermediate is obtained, namely cis-3-methyl-4-aminotetrahydropyran hydrochloride (compound I). The method is easy and convenient to operate and high in yield, the total yield can reach 40%, and rapid preparation in a laboratory can be achieved.

Chemoselective Oxidation of Equatorial Alcohols with N-Ligated λ3-Iodanes

Mikhael, Myriam,Adler, Sophia A.,Wengryniuk, Sarah E.

supporting information, p. 5889 - 5893 (2019/08/26)

The site-selective and chemoselective functionalization of alcohols in complex polyols remains a formidable synthetic challenge. Whereas significant advancements have been made in selective derivatization at the oxygen center, chemoselective oxidation to the corresponding carbonyls is less developed. In cyclic systems, whereas the selective oxidation of axial alcohols is well known, a complementary equatorial selective process has not yet been reported. Herein we report the utility of nitrogen-ligated (bis)cationic λ3-iodanes (N-HVIs) for alcohol oxidation and their unprecedented levels of selectivity for the oxidation of equatorial over axial alcohols. The conditions are mild, and the simple pyridine-ligated reagent (Py-HVI) is readily synthesized from commercial PhI(OAc)2 and can be either isolated or generated in situ. Conformational selectivity is demonstrated in both flexible 1,2-substituted cyclohexanols and rigid polyol scaffolds, providing chemists with a novel tool for chemoselective oxidation.

AMINO-QUINOLINES AS KINASE INHIBITORS

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Page/Page column 60; 61, (2018/06/22)

Disclosed are compounds having the formula:wherein R 1 , R 2 , R 3 and Z are as defined herein, and methods of making and using the same.

NRF2 ACTIVATOR

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Page/Page column 120, (2018/07/29)

Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, and methods for their use and production.

AMINO-QUINOLINES AS KINASE INHIBITORS

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Page/Page column 70; 71, (2018/05/15)

Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.

ANTI-BACTERIAL COMPOUNDS

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Page/Page column 115, (2017/06/28)

A compound of Formula (II): for use in the prevention or treatment of a bacterial infection.

AMINO-QUINOLINES AS KINASE INHIBITORS

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Paragraph 0129, (2016/10/31)

Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.

TBK/IKK INHIBITOR COMPOUNDS AND USES THEREOF

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Paragraph 0330; 0331, (2017/01/23)

The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as TBK/IKKε inhibitors.

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