A new method for the synthesis of 2-substituted azetidines has been exploited.The method consists of (1) anodic acetoxylation of 1-(p-tolylsulfonyl)azetidine at the 2-position and (2) subsequent nucleophilic substitution of the acetoxyl group with nucleophiles such as trimethylsilyl cyanide, allyltrimethylsilane, 2-acetoxyfuran, and trimethyl phosphite.