1202033-17-7

Basic information

• Product Name: (2S,2'S,3S,3'S)-BIBOP
• Synonyms: (2S,2'S,3S,3'S)-BIBOP;(2S,2'S,3S,3'S)-3,3'-di-tert-butyl-2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole;(2S,2'S,3S,3'S)-3,3'-Bis(tert-butyl)-2,2',3,3'-tetrahydro-2,2'-bi-1,3-benzoxaphosphole;(2S,2'S,3S,3'S)-3,3'-Di-tert-butyl-2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole, 97% (>99% ee) (2S,2'S,3S,3'S)-BIBOP
• CAS NO: 1202033-17-7
• Molecular Formula: C22H28O2P2
• Molecular Weight: 386.4
• Mol File: 1202033-17-7.mol

Chemical Properties

• Boiling Point: 495.5±45.0 °C(Predicted)
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (2S,2'S,3S,3'S)-BIBOP(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,2'S,3S,3'S)-BIBOP(1202033-17-7)
• EPA Substance Registry System: (2S,2'S,3S,3'S)-BIBOP(1202033-17-7)

Safety Data

• Hazardous Substances Data: 1202033-17-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(2S,2'S,3S,3'S)-BIBOP is used as a research tool for studying the δ-opioid receptor and its role in pain management. Its strong analgesic effects and selectivity for the δ-opioid receptor make it a valuable asset in understanding opioid pharmacology and developing new therapeutic approaches for pain relief.
(2S,2'S,3S,3'S)-BIBOP is also used as a potential candidate for the development of novel analgesic drugs. Its reduced side effects compared to traditional opioid medications make it a promising option for addressing the need for safer and more effective pain management therapies.
Used in Research Applications:
(2S,2'S,3S,3'S)-BIBOP is used as a research compound to investigate the mechanisms of action and signaling pathways associated with the δ-opioid receptor. This knowledge can contribute to the advancement of pain management strategies and the discovery of new therapeutic targets for the treatment of chronic and acute pain conditions.

Upstream product

• 1202032-91-4 tert-butyl(2,6-dimethoxyphenyl)(methyl)phosphine oxide 
• 1202033-01-9 (R)-3-tert-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphole 3-oxide 
• 1202032-99-2 (R)-3-(tert-butyl)-3-oxido-2H-benzo[d][1,3]oxaphosphol-4-yl trifluoromethanesulfonate 
• 1202033-25-7 (R)-3-(tert-butyl)-4-hydroxy-2H-benzo[ d][1,3]oxaphosphole 3-oxide 
• 1202032-97-0 (R)-3-(tert-butyl)-3-oxido-2H-benzo[d][1,3]oxaphosphol-4-yl ((1S,2R,5S)-2-isopropyl-5-methylcyclohexyl) carbonate 
• 1202032-95-8 racemic 3-tert-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphol-4-ol oxide 
• 1202032-93-6 tert-butyl(2,6-dimethoxyphenyl)(iodomethyl)phosphine oxide 
• 151-10-0 1,3-Dimethoxybenzene 
• 1202033-09-7 (2S,2'S,3R,3'R)-3,3'-di-tert-butyl-2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole bisoxide 

Relevant articles and documents

NOVEL CHIRAL PHOSPHORUS LIGANDS

The invention relates to a series of novel chiral phosphorus ligands of formulae (Ia) and (Ib): wherein R, 1 - rR> 4 and X are as defined herein. The invention also relates to chiral metal complexes prepared with these chiral phosphorus ligands. The chira

Novel, tunable, and efficient chiral bisdihydrobenzooxaphosphole ligands for asymmetric hydrogenation

"Chemical Equation Presented" A series of novel, efficient, air-stable, and tunable chiral bisdihydrobenzooxaphosphole ligands (BIBOPs) were developed for rhodium-catalyzed hydrogenations of various functionalized olefins such as α-ary lenam ides, α-(acylamino)acrylic acid derivatives, β-(acylamino)acrylates, and dimethyl itaconate with excellent enantioselectivities (up to 99% ee) and reactivities (up to 2000 TON)