120237-76-5 Usage
Uses
Used in Pharmaceutical Industry:
5-Methyl-1,3-thiazole-4-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications. Its unique chemical structure allows for the creation of compounds with specific biological activities, making it valuable in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 5-METHYL-1,3-THIAZOLE-4-CARBOXYLIC ACID is utilized as a building block for the development of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, thereby contributing to increased crop yields and agricultural productivity.
Used in Research and Development:
5-Methyl-1,3-thiazole-4-carboxylic acid is employed as a research compound for exploring its biological activities, including anti-inflammatory and antimicrobial properties. Scientists use 5-METHYL-1,3-THIAZOLE-4-CARBOXYLIC ACID to investigate its potential applications in treating various diseases and infections, as well as to understand its mechanism of action.
Used in Chemical Synthesis:
As a versatile chemical compound, 5-METHYL-1,3-THIAZOLE-4-CARBOXYLIC ACID is used in chemical synthesis for the production of a range of organic compounds. Its reactivity and functional groups make it a suitable candidate for various chemical reactions, leading to the formation of new compounds with diverse applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 120237-76-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,2,3 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 120237-76:
(8*1)+(7*2)+(6*0)+(5*2)+(4*3)+(3*7)+(2*7)+(1*6)=85
85 % 10 = 5
So 120237-76-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H5NO2S/c1-3-4(5(7)8)6-2-9-3/h2H,1H3,(H,7,8)
120237-76-5Relevant articles and documents
FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF
-
, (2009/06/27)
The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof. A compound represented by the formula (I): wherein each symbol is as defined in the specification, except a particular compound, or a salt thereof, and a pharmaceutical agent containing the compound or a prodrug thereof, which is a kinase (VEGFR, VEGFR2, PDGFR, Raf) inhibitor, an angiogenesis inhibitor, an agent for the prophylaxis or treatment of cancer, a cancer growth inhibitor or a cancer metastasis suppressor.
Identification of potent type I MetAP inhibitors by simple bioisosteric replacement. Part 1: Synthesis and preliminary SAR studies of thiazole-4-carboxylic acid thiazol-2-ylamide derivatives
Cui, Yong-Mei,Huang, Qing-Qing,Xu, Jie,Chen, Ling-Ling,Li, Jing-Ya,Ye, Qi-Zhuang,Li, Jia,Nan, Fa-Jun
, p. 3732 - 3736 (2007/10/03)
A series of thiazole-4-carboxylic acid thiazol-2-ylamide (TCAT, 4) derivatives were designed and synthesized according to simple bioisosteric replacement from previously reported pyridine-2-carboxylic acid thiazol-2-ylamide (PCAT) MetAP inhibitors. The preliminary SAR studies demonstrated that these TCAT series of compounds showed different activity and selectivity compared with those of the corresponding PCAT compounds. These findings provide useful information for the design and discovery of more potent inhibitors of type I MetAPs.
