SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
-
Paragraph 0459; 0460
(2015/12/25)
SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
-
Paragraph 0241
(2013/07/19)
Synthesis and Reactions of Isoquinoline Derivatives II. Synthesis of 3-Chloroisoquinoline-4-aldehydes
1-Aryl-substituted 1,4-dihydro-3(2H)isoquinolinones 1 are easily converted to 1-aryl-3-chloroisoquinoline-4-aldehydes 3 by a two-step procedure involving a Vilsmeier-Haack reaction followed by subsequent oxidation with potassium permanganate under acidic
Bartmann, W.,Konz, E.,Rueger, W.
p. 680 - 683
(2007/10/02)
More Articles about upstream products of 120285-29-2