120285-29-2 Usage
General Description
3-Chloroisoquinoline-4-carbaldehyde is a chemical compound with the molecular formula C10H6ClNO. It is an aldehyde derivative of isoquinoline, with a chlorine atom attached to the third carbon of the isoquinoline ring. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has also been studied for its potential biological and pharmacological activities, including its role as a potential antitumor agent. Additionally, 3-Chloroisoquinoline-4-carbaldehyde is known for its ability to act as a fluorescent probe for the detection of biologically important molecules, making it a valuable tool for chemical and biological research.
Check Digit Verification of cas no
The CAS Registry Mumber 120285-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,2,8 and 5 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 120285-29:
(8*1)+(7*2)+(6*0)+(5*2)+(4*8)+(3*5)+(2*2)+(1*9)=92
92 % 10 = 2
So 120285-29-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H6ClNO/c11-10-9(6-13)8-4-2-1-3-7(8)5-12-10/h1-6H
120285-29-2Relevant articles and documents
SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION
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Paragraph 0459; 0460, (2015/12/25)
Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
Synthesis and Reactions of Isoquinoline Derivatives II. Synthesis of 3-Chloroisoquinoline-4-aldehydes
Bartmann, W.,Konz, E.,Rueger, W.
, p. 680 - 683 (2007/10/02)
1-Aryl-substituted 1,4-dihydro-3(2H)isoquinolinones 1 are easily converted to 1-aryl-3-chloroisoquinoline-4-aldehydes 3 by a two-step procedure involving a Vilsmeier-Haack reaction followed by subsequent oxidation with potassium permanganate under acidic
