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120373-36-6

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Processes for the preparation of isomer free prostaglandins
Novel processes for the preparation of a compound of Formula I-2 substantially free of the 5,6-trans isomer: wherein R2, R3 and R4 are as defined in the specification are provided. Novel intermediates for the preparations of isomer free Prostaglandins and derivatives thereof are also provided.
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Paragraph 0241; 0242

(2015/03/03)

PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF ISOMER FREE PROSTAGLANDINS
Novel processes for the preparation of a compound of Formula I-2 substantially free of the 5,6-trans isomer: wherein R2, R3 and R4 are as defined in the specification are provided. Novel intermediates for the preparations of isomer free Prostaglandins and derivatives thereof are also provided.
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Paragraph 0051; 0241; 0242; 0244; 0245

(2015/02/25)

Treatment of cataract with 15-keto-prostaglandin compounds
A compound for treatment of a cataract which is a 15-ketoprostaglandin compound.
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(2008/06/13)

Chemical Properties

Boiling Point: 562.9°Cat760mmHg
Flash Point:308.3°C
Density: 1.069g/cm³
Vapor Pressure: 5.16E-15mmHg at 25°C
PKA: 4.76±0.10(Predicted)
PSA: 94.83000
LogP: 4.25530

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