1204295-87-3

Basic information

• Product Name: 2-Bromo-4-(difluoromethyl)pyridine
• Synonyms: 2-Bromo-4-(difluoromethyl)pyridine;2-Bromo-alpha,alpha-difluoro-4-picoline
• CAS NO: 1204295-87-3
• Molecular Formula: C6H4BrF2N
• Molecular Weight: 208.0034664
• Mol File: 1204295-87-3.mol

Chemical Properties

• Boiling Point: 243.1±35.0 °C(Predicted)
• Flash Point: 103℃
• Appearance: /
• Density: 1.657
• Refractive Index: 1.520
• Storage Temp.: ?20°C
• PKA: -0.88±0.26(Predicted)
• CAS DataBase Reference: 2-Bromo-4-(difluoromethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4-(difluoromethyl)pyridine(1204295-87-3)
• EPA Substance Registry System: 2-Bromo-4-(difluoromethyl)pyridine(1204295-87-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• WGK Germany: 1
• Hazardous Substances Data: 1204295-87-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-4-(difluoromethyl)pyridine is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-4-(difluoromethyl)pyridine serves as an intermediate in the production of agrochemicals. Its incorporation into these products can enhance their effectiveness in agricultural applications.
Used in Specialty Chemicals Production:
2-Bromo-4-(difluoromethyl)pyridine is utilized as an intermediate in the manufacturing process of specialty chemicals. Its role in this industry is vital for creating high-quality and specialized chemical products.
Used as a Reagent in Organic Synthesis:
2-Bromo-4-(difluoromethyl)pyridine also functions as a reagent in organic synthesis. Its reactivity and structural features make it a valuable tool for chemists in conducting various organic reactions and syntheses.

Upstream product

• 118289-17-1 2-bromopyridine-4-carboxaldehyde 

Downstream Products

• 1419221-56-9 N-(4-(difluoromethyl)pyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 

Relevant articles and documents

SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME

The present disclosure includes substituted tricyclic amides, or analogues thereof of formula (I) (I), wherein X, Y, ring A, R1, R5, R6 and R7 are as defined herein, and compositions comprising compounds of formula (I) that can be used to treat or prevent hepatitis B virus (HBV) and/or hepatitis D virus (HDV) infections in a patient.

BTK INHIBITORS

The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds in the treatment of Btk mediated disorders.

BTK INHIBITORS

The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds in the treatment of Btk mediated disorders.

BTK INHIBITORS

The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I) or pharmaceutically acceptable salts thereof. (Formula I) or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds in the treatment of Btk mediated disorders.