120444-72-6

Basic information

• Product Name: deramciclane
• Synonyms: (1R-exo)-N,N-Dimethyl-2-((1,7,7-trimethyl-2-phenylbicyclo[2.2.1]hept-2-yl)oxy)ethanamine (E)-2-Butenedioate (1:1); 120444-72-6; N,N-Dimethyl-2-{[(1R,2S,4R)-1,7,7-trimethyl-2-phenylbicyclo[2.2.1]hept-2-yl]oxy}ethanamine (2E)-but-2-enedioate (1:1); N,N-dimethyl-2-{[(1R,2S,4R)-1,7,7-trimethyl-2-phenylbicyclo[2.2.1]hept-2-yl]oxy}ethanamine (2E)-but-2-enedioate
• CAS NO: 120444-72-6
• Molecular Formula: C₄H₄O₄*C₂₀H₃₁NO
• Molecular Weight: 417.543
• Mol File: 120444-72-6.mol

Chemical Properties

• Melting Point: 210-213°
• Boiling Point: 375.2°Cat760mmHg
• Flash Point: 110.6°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 7.93E-06mmHg at 25°C
• PKA: 9.61(at 25℃)
• CAS DataBase Reference: deramciclane(CAS DataBase Reference)
• NIST Chemistry Reference: deramciclane(120444-72-6)
• EPA Substance Registry System: deramciclane(120444-72-6)

Safety Data

• Hazardous Substances Data: 120444-72-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H31NO.C4H4O4/c1-18(2)17-11-12-19(18,3)20(15-17,22-14-13-21(4)5)16-9-7-6-8-10-16;5-3(6)1-2-4(7)8/h6-10,17H,11-15H2,1-5H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t17-,19-,20+;/m1./s1

Upstream product

• 120444-71-5 deramciclane 
• 108-86-1 bromobenzene 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 

Relevant articles and documents

High purity (1R,2S,4R)-(-)-2-[(2′-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof

The invention relates to high purity (1R,2S,4R)-(?)-2-[(2′-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2′-{N,N

Process for preparing (1R,2S,4R)-(-)-2-[(2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof

A process for preparing (1R,2S,4R)-(?)-2-[(2′-[N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo [2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof with higher yields and higher grades of purity.

Process for preparing (1R, 2S, 4R)-(-)-2-[(2'-(N,N-dimethylamino)-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof

The invention relates to a process for preparing (1R,2S,4R)-(-)-2-[(2'-{N,N-dimethylamino}-ethoxy)]-2--[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof with higher yields and higher grades of pu