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1204707-71-0

SRT3109 is a CXCR2 ligand and a potent chemoattractant for neutrophils, which are essential immune cells in the body. It is a small molecule that can modulate the activity of the CXCR2 receptor, which plays a crucial role in various physiological and pathological processes.

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  • 1204707-71-0 Structure

  • Basic information

    1. Product Name: SRT3109
    2. Synonyms: N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide;SRT3109;N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1R,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide
    3. CAS NO:1204707-71-0
    4. Molecular Formula: C18H23F2N5O4S2
    5. Molecular Weight: 475.5331264
    6. EINECS: N/A
    7. Product Categories: Inhibitors
    8. Mol File: 1204707-71-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.55
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: SRT3109(CAS DataBase Reference)
    10. NIST Chemistry Reference: SRT3109(1204707-71-0)
    11. EPA Substance Registry System: SRT3109(1204707-71-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1204707-71-0(Hazardous Substances Data)

1204707-71-0 Usage

Uses

Used in Pharmaceutical Industry:
SRT3109 is used as a therapeutic agent for the treatment of various inflammatory and immune-related disorders. Its ability to modulate the CXCR2 receptor makes it a promising candidate for the development of new drugs targeting conditions such as chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), and sepsis.
Used in Research Applications:
SRT3109 is also used as a research tool to study the role of CXCR2 in various biological processes. It can be employed in in vitro and in vivo experiments to investigate the effects of CXCR2 modulation on neutrophil function, inflammation, and immune response.
Used in Drug Delivery Systems:
Similar to gallotannin, SRT3109 can be incorporated into novel drug delivery systems to enhance its applications and efficacy. These systems can be designed to improve the delivery, bioavailability, and therapeutic outcomes of SRT3109, particularly in the context of treating inflammatory and immune-related disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 1204707-71-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,4,7,0 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1204707-71:
(9*1)+(8*2)+(7*0)+(6*4)+(5*7)+(4*0)+(3*7)+(2*7)+(1*1)=120
120 % 10 = 0
So 1204707-71-0 is a valid CAS Registry Number.

1204707-71-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2R,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide

1.2 Other means of identification

Product number -
Other names Y0301

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1204707-71-0 SDS

1204707-71-0Downstream Products

1204707-71-0Relevant articles and documents

NOVEL COMPOUND 395

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Page/Page column 14, (2010/02/17)

A compound of formula (1) and pharmaceutically acceptable salts thereof for use in the treatment of chemokine mediated diseases and conditions.

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