120491-90-9

Basic information

• Product Name: Diethyl 4-iodo-2,6-pyridinedicarboxylate
• Synonyms: Diethyl 4-iodo-2,6-pyridinedicarboxylate;4-Iodopyridine-2,6-dicarboxylic acid diethyl ester;diethyl 4-iodopyridine-2,6-dicarboxylate
• CAS NO: 120491-90-9
• Molecular Formula: C₁₁H₁₂INO₄
• Molecular Weight: 349.12
• Mol File: 120491-90-9.mol

Chemical Properties

• Boiling Point: 417.2°C at 760 mmHg
• Flash Point: 206.1°C
• Appearance: /
• Density: 1.635g/cm³
• Vapor Pressure: 3.59E-07mmHg at 25°C
• Refractive Index: 1.57
• PKA: -2.10±0.10(Predicted)
• CAS DataBase Reference: Diethyl 4-iodo-2,6-pyridinedicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Diethyl 4-iodo-2,6-pyridinedicarboxylate(120491-90-9)
• EPA Substance Registry System: Diethyl 4-iodo-2,6-pyridinedicarboxylate(120491-90-9)

Safety Data

• Hazardous Substances Data: 120491-90-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Diethyl 4-iodo-2,6-pyridinedicarboxylate is used as a pharmaceutical intermediate for the synthesis of various drugs and pharmaceuticals. Its unique structure and reactivity make it a valuable building block in the development of new medications with potential therapeutic applications.
Used in Organic Synthesis:
Diethyl 4-iodo-2,6-pyridinedicarboxylate is used as a reagent in organic synthesis reactions due to its solubility in organic solvents and its ability to undergo various chemical transformations. This allows chemists to create a wide range of new compounds with diverse chemical properties and potential applications.
Used in Derivatization:
The presence of the diethyl ester groups in Diethyl 4-iodo-2,6-pyridinedicarboxylate makes it suitable for further derivatization to create new compounds with potential bioactive properties. This can lead to the development of novel pharmaceuticals, agrochemicals, or other specialty chemicals with unique functions and benefits.

InChI:InChI=1/C11H12INO4/c1-3-16-10(14)8-5-7(12)6-9(13-8)11(15)17-4-2/h5-6H,3-4H2,1-2H3

Upstream product

• 112776-83-7 diethyl 4-bromo-2,6-pyridinedicarboxylate 
• 53389-01-8 diethyl 4-chloropyridine-2,6-dicarboxylate 
• 499-51-4 Chelidamic acid 
• 71022-75-8 4-chloropyridine-2,6-dicarbonyl dichloride 

Downstream Products

• 1425509-99-4 diethyl 6,6'-((((4-((4-aminophenyl)ethynyl)pyridine-2,6-diyl)bis(methylene))bis((2-ethoxy-2-oxoethyl)azanediyl))bis(methylene))bis(4-bromopicolinate) 
• 106967-33-3 4-iodo-2,6-bis(bromomethyl)pyridine 
• 120491-91-0 2,6-bis(hydroxymethyl)-4-iodopyridine 

Relevant articles and documents

An efficient triazole-pyridine-bistetrazolate platform for highly luminescent lanthanide complexes

Two new triazole-pyridine-bistetrazolate ligands were synthesized via a versatile procedure that allows for further derivatization; their corresponding homoleptic tris-ligand nona-coordinated lanthanide complexes are highly luminescent in the solid state and in a PVA polymeric matrix with measured values for the luminescence quantum yield of 70(7) and 98(9)% for Eu III and TbIII, respectively. This journal is the Partner Organisations 2014.

Luminescent Carbazole-Based EuIII and YbIII Complexes with a High Two-Photon Absorption Cross-Section Enable Viscosity Sensing in the Visible and near IR with One- And Two-Photon Excitation

The newly synthesized EuIII and YbIII complexes with the new carbazole-based ligands CPAD2- and CPAP4- display the characteristic long-lived metal-centered emission upon one- and two-photon excitation. The EuIII complexes show the expected narrow emission bands in the red region, with emission lifetimes between 0.382 and 1.464 ms and quantum yields between 2.7% and 35.8%, while the YbIII complexes show the expected emission in the NIR region, with emission lifetimes between 0.52 and 37.86 μs and quantum yields between 0.028% and 1.12%. Two-photon absorption cross sections (σ2PA) as high as 857 GM were measured for the two ligands. The complexes showed a strong dependence of the one- and two-photon sensitized emission intensity on solvent viscosity in the range of 0.5-200 cP in the visible and NIR region.

NOVEL 5 OR 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES

Disclosed herein are 5 or 8-substituted imidazo[l,5-a]pyridines and pharmaceutical compositions comprising at least one such 5 or 8-substituted imidazo[l,5-a]pyridines, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain 5 or 8- substituted imidazo[l,5-a]pyridines that can be useful for inhibiting indoleamine 2,3- dioxygenase and/or tryptophane 2,3-dioxygenase and for treating diseases or disorders mediated thereby.

LUMINESCENT LANTHANIDE (III) CHELATES, CHELATING AGENTS AND CONJUGATES DERIVED THEREOF

This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the inve