120550-58-5

Basic information

• Product Name: Hydrazine,cyclopropyl-
• Synonyms: Hydrazine,cyclopropyl-;CYCLOPROPYLHYDRAZINE. HCl;EOS-62323
• CAS NO: 120550-58-5
• Molecular Formula: C3H8N2
• Molecular Weight: 72.10902
• EINECS: -0
• Mol File: 120550-58-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Hydrazine,cyclopropyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazine,cyclopropyl-(120550-58-5)
• EPA Substance Registry System: Hydrazine,cyclopropyl-(120550-58-5)

Safety Data

• Hazardous Substances Data: 120550-58-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Hydrazine, cyclopropylis used as a raw material for the production of various pharmaceuticals. Its unique chemical properties make it a valuable component in the synthesis of drugs with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, hydrazine, cyclopropylserves as a key ingredient in the manufacturing of certain pesticides and other agricultural chemicals. Its reactivity contributes to the development of effective products for crop protection and enhancement.
Used in Organic Synthesis:
Hydrazine, cyclopropylis utilized as a reagent in organic synthesis, where it plays a crucial role in various chemical reactions. Its ability to form different chemical bonds makes it instrumental in creating a wide range of organic compounds.
Used in Aerospace Industry:
As a propellant in rocket fuel, hydrazine, cyclopropylcontributes to the performance of propulsion systems in the aerospace industry. Its high energy content and combustion properties make it suitable for use in space exploration and satellite launches.
Despite its significant applications, the hazardous nature of hydrazine, cyclopropylrequires strict adherence to safety measures to minimize health risks to humans and protect the environment.

Upstream product

• 844872-72-6 1,1-dimethylethyl cyclopropyl(nitroso)carbamate 
• 1219020-59-3 tert-butyl N-(tert-butoxycarbonylamino)-N-cyclopropyl-carbamate 
• 848153-29-7 N'-cyclopropyl-hydrazinecarboxylic acid tert-butyl ester 

Relevant articles and documents

BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS

Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula I as follows: Formula I wherein R1, R2, R3, and Q are defined herein.

Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators

The present study describes the discovery and characterization of a series of 5-aryl-2H-tetrazol-3-ylacetamides as G protein-gated inwardly-rectifying potassium (GIRK) channels activators. Working from an initial hit discovered during a high-throughput screening campaign, we identified a tetrazole scaffold that shifts away from the previously reported urea-based scaffolds while remaining effective GIRK1/2 channel activators. In addition, we evaluated the compounds in Tier 1 DMPK assays and have identified a (3-methyl-1H-pyrazol-1-yl)tetrahydrothiophene-1,1-dioxide head group that imparts interesting and unexpected microsomal stability compared to previously-reported pyrazole head groups.

Pyrazolopyrrolidine Derivatives and their Use in the Treatment of Disease

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

PYRAZOLOPYRROLIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

AZAINDAZOLES

Herein are disclosed azaindazoles of formula (I), (I), where the various groups are defined herein, and which are useful for treating cancer.